TcCLB.506659.39

protein phosphatase 2C, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_122898 OG7: OG7_0000783 301 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 301 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503813.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509453.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508131.19 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
TcCLB.506357.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510771.9 ⚠
Thioredoxin-like/Protein of unknown function
— OG7
TcCLB.510773.9 ⚠
Thioredoxin-like/Protein of unknown function
— OG7
TcCLB.507811.120 ⚠
myosin heavy chain MYA2-related, putative
— OG7
TcCLB.464807.10 ⚠
serine/threonine protein kinase, putative, CA
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.510143.40 ⚠
UBX domain-containing protein
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506925.70 ⚠
epsin, putative
— OG7
TcCLB.503905.10 ⚠
myosin heavy chain, putative
— OG7
TcCLB.506779.190 ⚠
Unconventional myosin
— OG7
TcCLB.507445.50 ⚠
myosin heavy chain, putative
— OG7
TcCLB.506925.319 ⚠
isocitrate dehydrogenase, putative
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.506357.50 ⚠
alcohol dehydrogenase, putative
— OG7
TcCLB.482369.29 ⚠
arginine kinase (fragment)
— OG7
TcCLB.506755.20 ⚠
paraflagellar rod component, putative
— OG7
TcCLB.504867.120 ⚠
hypothetical protein
— OG7
TcCLB.511589.140 ⚠
PEP mutase, putative, phosphoenolpyruvate mut
— OG7
TcCLB.510861.140 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.508465.10 ⚠
aminotransferase, putative
— OG7
TcCLB.507837.90 ⚠
cell division cycle protein, putative
— OG7
TcCLB.509199.10 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.505989.74 ⚠
peroxisome biogenesis factor 1, putative
— OG7
TcCLB.507093.210 ⚠
myosin heavy chain, putative
— OG7
TcCLB.507611.340 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509205.110 ⚠
elongation factor G2-like protein, putative
— OG7
TcCLB.510257.130 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.506635.60 ⚠
pyroglutamyl-peptidase I, putative
— OG7
TcCLB.506947.40 ⚠
peroxisome assembly protein, putative
— OG7
TcCLB.506747.20 ⚠
dihydroorotase, putative
— OG7
TcCLB.510719.60 ⚠
Biotin--acetyl-CoA-carboxylase ligase, putati
— OG7
TcCLB.506795.44 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG7
TcCLB.511537.69 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510525.10 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcCLB.511911.130 ⚠
phosphoglucomutase
— OG7
TcCLB.506367.180 ⚠
vesicular transport protein (CDC48 homologue)
— OG7
TcCLB.508387.70 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
TcCLB.506811.190 ⚠
UDP-galactose 4-epimerase
— OG7
TcCLB.510323.20 ⚠
Flagellum attachment zone protein 19, putativ
— OG7
TcCLB.509165.49 ⚠
damage-specific DNA binding protein, putative
— OG7
TcCLB.506945.359 ⚠
damage-specific DNA binding protein, putative
— OG7
TcCLB.506359.60 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— OG7
TcCLB.511419.50 ⚠
3-phosphoglycerate kinase, glycosomal
— OG7
TcCLB.506949.20 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.