TcCLB.507611.340

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_146958 OG7: OG7_0037735 94 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 94 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509801.30
citrate synthase, putative
— Both
TcCLB.511555.110
Domain of unknown function (DUF4486), putativ
— OG7
TcCLB.510073.50 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— OG7
TcCLB.506637.30 ⚠
Protein of unknown function (DUF3808), putati
— OG7
TcCLB.509979.40
Zn-finger in Ran binding protein and others/S
— Both
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— Both
TcCLB.508323.100
I/6 autoantigen, putative
— Both
TcCLB.508265.110 ⚠
hypothetical protein, conserved
— Both
TcCLB.508389.130 ⚠
Mucin-associated surface protein (MASP), subg
— OG6
TcCLB.510405.9 ⚠
hypothetical protein, conserved (fragment)
— Both
TcCLB.507747.110 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.405165.19 ⚠
hypothetical protein, conserved (fragment)
— Both
TcCLB.511001.130
hypothetical protein, conserved
— OG7
TcCLB.510089.200
Eukaryotic translation initiation factor 3 su
— Both
TcCLB.506529.490
hypothetical protein, conserved
— Both
TcCLB.508321.40
Tripartite attachment complex protein 102
— Both
TcCLB.506945.330 ⚠
Protein of unknown function (DUF3808), putati
— Both
TcCLB.507611.310
eukaryotic translation initiation factor 3 su
— Both
TcCLB.506685.50 ⚠
myosin heavy chain, putative (fragment)
— Both
TcCLB.511527.70 ⚠
Unconventional myosin
— Both
TcCLB.509497.20
hypothetical protein, conserved
— Both
TcCLB.511539.9 ⚠
hypothetical protein, conserved
— Both
TcCLB.507811.120 ⚠
myosin heavy chain MYA2-related, putative
— Both
TcCLB.504103.30 ⚠
myosin heavy chain, putative
— Both
TcCLB.509951.10 ⚠
nucleolar protein, putative
— OG7
TcCLB.509831.5 ⚠
vesicular transport protein (CDC48 homologue)
— OG7
TcCLB.511745.20 ⚠
AAA ATPase, putative
— OG7
TcCLB.507445.50 ⚠
myosin heavy chain, putative
— OG7
TcCLB.507837.90 ⚠
cell division cycle protein, putative
— OG7
TcCLB.505989.74 ⚠
peroxisome biogenesis factor 1, putative
— OG7
TcCLB.507093.210 ⚠
myosin heavy chain, putative
— OG7
TcCLB.506947.40 ⚠
peroxisome assembly protein, putative
— OG7
TcCLB.506367.180 ⚠
vesicular transport protein (CDC48 homologue)
— OG7
TcCLB.506925.410 ⚠
ATPase, putative
— OG7
TcCLB.507739.110 ⚠
myosin IB heavy chain, putative
— OG7
TcCLB.510089.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510075.50
hypothetical protein, conserved
— Both
TcCLB.507257.20 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.506467.29 ⚠
methyltransferase domain containing protein,
— OG7
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG7
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— OG7
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.511627.140
hypothetical protein, conserved
— Both
TcCLB.508541.225 ⚠
casein kinase, putative
— OG6
TcCLB.504929.15 ⚠
casein kinase, delta isoform, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.