TcCLB.510089.200

Eukaryotic translation initiation factor 3 subunit F
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_147150 OG7: OG7_0043510 69 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 69 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.508389.130 ⚠
Mucin-associated surface protein (MASP), subg
— OG6
TcCLB.507811.120 ⚠
myosin heavy chain MYA2-related, putative
— OG7
TcCLB.506795.100 ⚠
hypothetical protein
— OG7
TcCLB.504103.30 ⚠
myosin heavy chain, putative
— OG7
TcCLB.504227.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504883.60
hypothetical protein, conserved
— OG7
TcCLB.511131.80
hypothetical protein, conserved
— OG7
TcCLB.509267.40
eukaryotic translation initiation factor 3 su
— Both
TcCLB.508265.110 ⚠
hypothetical protein, conserved
— Both
TcCLB.507795.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510405.9 ⚠
hypothetical protein, conserved (fragment)
— Both
TcCLB.507747.110 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.405165.19 ⚠
hypothetical protein, conserved (fragment)
— Both
TcCLB.508307.44
pre-mRNA splicing factor 46, putative
— Both
TcCLB.506811.150
hypothetical protein, conserved
— Both
TcCLB.511627.140
hypothetical protein, conserved
— Both
TcCLB.506943.160
eukaryotic translation initiation factor 3 su
— Both
TcCLB.509167.180
kinesin, putative
— OG6
TcCLB.511527.70 ⚠
Unconventional myosin
— OG7
TcCLB.511365.90
hypothetical protein, conserved
— OG7
TcCLB.506147.150 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
TcCLB.508357.100 ⚠
Serine-threonine kinase receptor-associated p
— OG7
TcCLB.510533.170
hypothetical protein, conserved
— OG7
TcCLB.511555.110
Domain of unknown function (DUF4486), putativ
— OG7
TcCLB.510073.50 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— OG7
TcCLB.507093.72
repressor activator protein 1
— OG7
TcCLB.506685.50 ⚠
myosin heavy chain, putative (fragment)
— OG7
TcCLB.511109.30 ⚠
dynein intermediate chain, putative
— Both
TcCLB.507669.70 ⚠
Dynein intermediate chain 1, axonemal
— OG7
TcCLB.503905.10 ⚠
myosin heavy chain, putative
— OG7
TcCLB.506779.190 ⚠
Unconventional myosin
— OG7
TcCLB.507445.50 ⚠
myosin heavy chain, putative
— OG7
TcCLB.504867.120 ⚠
hypothetical protein
— OG7
TcCLB.511001.130
hypothetical protein, conserved
— OG7
TcCLB.507093.210 ⚠
myosin heavy chain, putative
— OG7
TcCLB.506599.10 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— Both
TcCLB.504247.79 ⚠
transmembrane protein, conserved (fragment)
— Both
TcCLB.511429.10 ⚠
transmembrane protein, conserved (fragment)
— Both
TcCLB.509205.30
Eukaryotic translation initiation factor 3 su
— Both
TcCLB.511589.230 ⚠
eukaryotic translation initiation factor 3 su
— Both
TcCLB.507975.80
eukaryotic translation initiation factor 3 su
— Both
TcCLB.506563.30
coatomer beta subunit, putative
— Both
TcCLB.509805.170 ⚠
pre-RNA processing PIH1/Nop17, putative
— Both
TcCLB.511363.4
hypothetical protein, conserved
— Both
TcCLB.504423.10 ⚠
hypothetical protein, conserved
— OG6
TcCLB.510163.20 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— Both
TcCLB.507237.110 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— Both
TcCLB.503977.79 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— Both
TcCLB.508163.150 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— Both
TcCLB.506603.50 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.