TcCLB.508357.100

Serine-threonine kinase receptor-associated protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_103369 OG7: OG7_0003947 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509205.30 ⚠
Eukaryotic translation initiation factor 3 su
— OG7
TcCLB.508169.90 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcCLB.511303.60 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcCLB.507611.310 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcCLB.506943.160 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcCLB.507975.80 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcCLB.505807.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509267.40 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcCLB.503749.10 ⚠
Serine hydrolase (FSH1)/RWD domain/50S riboso
— OG7
TcCLB.509099.10 ⚠
GTP-binding protein, putative
— OG7
TcCLB.511871.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508515.20 ⚠
Eukaryotic translation initiation factor 1, p
— OG7
TcCLB.506405.10 ⚠
phosphomannomutase-like protein, putative
— Both
TcCLB.503697.110 ⚠
Soluble NSF attachment protein, SNAP, putativ
— Both
TcCLB.511041.4 ⚠
Sucrase/ferredoxin-like, putative
— Both
TcCLB.508729.18 ⚠
Sucrase/ferredoxin-like, putative
— Both
TcCLB.511621.90 ⚠
esterase, putative
— Both
TcCLB.506147.100 ⚠
Spindle assembly abnormal protein 6 homolog
— OG7
TcCLB.506811.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510517.10 ⚠
chaperonin/T-complex protein 1 gamma subunit,
— OG7
TcCLB.504181.50 ⚠
T-complex protein 1, delta subunit, putative
— OG7
TcCLB.510515.139 ⚠
T-complex protein 1, gamma subunit, putative
— OG7
TcCLB.509583.10 ⚠
chaperonin TCP20, putative
— OG7
TcCLB.508357.90 ⚠
T-complex protein 1, beta subunit, putative
— OG7
TcCLB.511531.40 ⚠
chaperonin alpha subunit, putative
— OG7
TcCLB.510089.200 ⚠
Eukaryotic translation initiation factor 3 su
— OG7
TcCLB.511363.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511419.50 ⚠
3-phosphoglycerate kinase, glycosomal
— OG7
TcCLB.506893.80 ⚠
monothiol glutaredoxin, putative
— OG7
TcCLB.511711.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506861.39 ⚠
dephospho-CoA kinase, putative (fragment)
— OG6
TcCLB.503677.10 ⚠
phosphomannose isomerase, putative
— Both
TcCLB.511215.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.511715.10 ⚠
iron superoxide dismutase, putative
— Both
TcCLB.507603.30 ⚠
PITH domain-containing protein
— Both
TcCLB.511545.120 ⚠
superoxide dismutase, putative
— Both
TcCLB.509775.40 ⚠
iron superoxide dismutase A, mitochondrial
— Both
TcCLB.503897.40 ⚠
basal body component, putative
— Both
TcCLB.509475.10 ⚠
mitogen-activated protein kinase 3, putative
— OG6
TcCLB.507993.60 ⚠
hypothetical protein, conserved
— Both
TcCLB.506863.4 ⚠
dephospho-CoA kinase, putative
— OG6
TcCLB.506945.20 ⚠
PAS-domain containing phosphoglycerate kinase
— Both
TcCLB.507039.10 ⚠
iron superoxide dismutase, putative
— Both
TcCLB.511303.34 ⚠
Macro domain containing protein, putative
— Both
TcCLB.505945.5 ⚠
mitogen-activated protein kinase 3, putative
— OG6
TcCLB.504147.30 ⚠
Protein of unknown function (DUF2870), putati
— Both
TcCLB.511573.40
Mitogen-activated protein kinase 10, putative
— OG6
TcCLB.511419.40 ⚠
phosphoglycerate kinase, putative
— Both
TcCLB.503425.20 ⚠
monothiol glutaredoxin, putative
— Both
TcCLB.511179.100 ⚠
monothiol glutaredoxin, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.