TcCLB.511215.50

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_148250 OG7: OG7_0051961 167 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 167 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506635.60
pyroglutamyl-peptidase I, putative
— Both
TcCLB.503425.20 ⚠
monothiol glutaredoxin, putative
— Both
TcCLB.511179.100 ⚠
monothiol glutaredoxin, putative
— Both
TcCLB.506893.80 ⚠
monothiol glutaredoxin, putative
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.508347.130
deoxyhypusine hydroxylase, putative
— Both
TcCLB.506779.20
hypothetical protein, conserved
— Both
TcCLB.511577.40
35 kDa cyclophilin, putative, rotamase, putat
— OG6
TcCLB.511041.4 ⚠
Sucrase/ferredoxin-like, putative
— Both
TcCLB.511741.40
RNA-binding protein, putative
— OG6
TcCLB.510595.20 ⚠
KH domain/Domain of unknown function (DUF1771
— Both
TcCLB.511575.60 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TcCLB.511801.50
tRNA threonylcarbamoyl adenosine modification
— Both
TcCLB.511573.40
Mitogen-activated protein kinase 10, putative
— OG6
TcCLB.508373.20 ⚠
dihydroorotase, putative
— Both
TcCLB.509953.9 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcCLB.506591.20
U-box domain protein, putative
— Both
TcCLB.508955.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.507993.150
Activator of Hsp90 ATPase, N-terminal/Activat
— Both
TcCLB.506525.80
N-myristoyl transferase, putative
— Both
TcCLB.503685.30 ⚠
carnitine/choline acetyltransferase, putative
— Both
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— Both
TcCLB.507941.100
hypothetical protein, conserved
— Both
TcCLB.509453.4 ⚠
hypothetical protein, conserved
— Both
TcCLB.509551.70 ⚠
Co-chaperone protein P23
— Both
TcCLB.504147.30
Protein of unknown function (DUF2870), putati
— Both
TcCLB.511693.90
electron-transfer-flavoprotein, alpha polypep
— Both
TcCLB.506945.40 ⚠
hypothetical protein, conserved
— Both
TcCLB.508989.9 ⚠
nucleoside phosphorylase, putative
— Both
TcCLB.506865.2 ⚠
nucleoside phosphorylase, putative
— Both
TcCLB.509767.90
alanine racemase, putative
— Both
TcCLB.506625.140 ⚠
methyltransferase domain containing protein,
— Both
TcCLB.511115.40 ⚠
transcription elongation factor s-II, putativ
— Both
TcCLB.509769.63
Ran-binding protein, putative
— Both
TcCLB.511625.50 ⚠
GTP-binding protein, putative
— Both
TcCLB.511621.220 ⚠
esterase, putative
— Both
TcCLB.511621.90 ⚠
esterase, putative
— Both
TcCLB.508389.10 ⚠
methyltransferase domain containing protein,
— Both
TcCLB.509099.10 ⚠
GTP-binding protein, putative
— OG7
TcCLB.503749.10 ⚠
Serine hydrolase (FSH1)/RWD domain/50S riboso
— OG7
TcCLB.510777.29 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510939.9 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511351.41 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511353.4 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.505123.28 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.511145.80 ⚠
RNA polymerase II, putative
— OG7
TcCLB.506495.3 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.