TcCLB.506495.3

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_553083 OG7: OG7_0033971 215 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 215 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.504077.40 ⚠
translation elongation factor EF-2, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506691.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511353.40 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcCLB.506677.10 ⚠
ubiquitin-like protein, putative
— OG7
TcCLB.503893.60 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TcCLB.421959.10 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.506127.170 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcCLB.504935.10 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.503841.70 ⚠
aspartate aminotransferase, putative
— OG7
TcCLB.407477.30 ⚠
diphthine synthase, putative
— OG7
TcCLB.510777.29 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.503959.78 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506525.80 ⚠
N-myristoyl transferase, putative
— OG7
TcCLB.511307.6 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.509805.40 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
TcCLB.508463.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506949.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506359.60 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— OG7
TcCLB.510311.90 ⚠
quinone oxidoreductase, putative
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.504147.30 ⚠
Protein of unknown function (DUF2870), putati
— OG7
TcCLB.507993.390 ⚠
pyruvate kinase 2, putative
— OG7
TcCLB.506931.10 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.507165.59 ⚠
Protein of unknown function (DUF2009), putati
— OG7
TcCLB.507817.80 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG7
TcCLB.511305.10 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcCLB.506351.9 ⚠
5'-3' exoribonuclease A, putative (fragment)
— OG7
TcCLB.507641.80 ⚠
5'-3' exoribonuclease D, putative
— OG7
TcCLB.505807.180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.509965.330 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510323.20 ⚠
Flagellum attachment zone protein 19, putativ
— OG7
TcCLB.508347.130 ⚠
deoxyhypusine hydroxylase, putative
— OG7
TcCLB.510283.70 ⚠
glycosyl hydrolase-like protein, putative
— OG7
TcCLB.508383.10 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcCLB.507993.150 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG7
TcCLB.511215.50 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.