TcCLB.503893.60

UBA/TS-N domain containing protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_129093 OG7: OG7_0004831 173 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 173 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.505807.180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511575.60 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TcCLB.511573.40
Mitogen-activated protein kinase 10, putative
— OG6
TcCLB.508373.20 ⚠
dihydroorotase, putative
— Both
TcCLB.506591.20 ⚠
U-box domain protein, putative
— Both
TcCLB.507993.150 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— Both
TcCLB.508955.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.506525.80 ⚠
N-myristoyl transferase, putative
— Both
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— Both
TcCLB.510859.24 ⚠
hypothetical protein, conserved
— Both
TcCLB.507941.100 ⚠
hypothetical protein, conserved
— Both
TcCLB.509453.4 ⚠
hypothetical protein, conserved
— Both
TcCLB.509551.70 ⚠
Co-chaperone protein P23
— Both
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— Both
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcCLB.506895.40 ⚠
Kinesin-13 1, putative
— OG7
TcCLB.509589.30 ⚠
Kinesin-13 5, putative
— OG7
TcCLB.508921.30 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.505123.28 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.510841.10 ⚠
Kinesin-13 4b, putative (fragment)
— OG7
TcCLB.504153.290 ⚠
diphthamide biosynthesis enzyme Dph1/Dph2 dom
— OG7
TcCLB.507993.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511627.120 ⚠
aldo/keto reductase, putative
— OG7
TcCLB.510101.140 ⚠
pyruvate phosphate dikinase, putative
— OG7
TcCLB.511001.240 ⚠
proteasome activator protein pa26, putative
— OG7
TcCLB.504867.20 ⚠
ABC transporter, putative
— OG7
TcCLB.510743.10 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.503841.10 ⚠
proteasome activator protein pa26, putative
— OG7
TcCLB.506659.30 ⚠
glutathione synthetase, putative
— OG7
TcCLB.504427.250 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.504867.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506737.20 ⚠
CMGC/MAPK protein kinase, putative
— OG7
TcCLB.510603.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510741.229 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.506743.170 ⚠
Met-10+ like-protein, putative
— OG7
TcCLB.511303.40 ⚠
carnitine O-acetyltransferase, putative
— OG7
TcCLB.507211.10 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511353.4 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511351.41 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.511305.10 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcCLB.506239.20 ⚠
Metallopeptidase family M24, putative
— OG7
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.510257.130 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.509205.110 ⚠
elongation factor G2-like protein, putative
— OG7
TcCLB.506857.90 ⚠
proteasome regulatory ATPase subunit 1, putat
— OG7
TcCLB.509199.10 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
Page 1 of 4
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.