TcCLB.506659.30

glutathione synthetase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101596 OG7: OG7_0006266 71 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 71 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507529.50
Ankyrin repeats (3 copies), putative
— Both
TcCLB.510055.60
Probable N6-adenine methyltransferase, putati
— Both
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511867.190 ⚠
tubulin gamma chain
— OG7
TcCLB.503969.10 ⚠
tubulin delta chain
— OG7
TcCLB.509967.160 ⚠
epsilon tubulin, putative
— OG7
TcCLB.506733.140
hypothetical protein, conserved
— OG7
TcCLB.506739.50 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TcCLB.506677.10 ⚠
ubiquitin-like protein, putative
— OG7
TcCLB.503893.60 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TcCLB.511707.39 ⚠
Importin subunit beta-4, putative
— OG7
TcCLB.504867.20
ABC transporter, putative
— OG7
TcCLB.504625.80
hypothetical protein, conserved
— Both
TcCLB.506737.20
CMGC/MAPK protein kinase, putative
— Both
TcCLB.506743.170 ⚠
Met-10+ like-protein, putative
— Both
TcCLB.510741.229 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcCLB.511745.10 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TcCLB.510603.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.508095.20 ⚠
mRNA cap methyltransferase-like protein, puta
— Both
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— Both
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.504867.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510963.30 ⚠
cap guanine-N7 methyltransferase
— OG7
TcCLB.503479.49 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcCLB.510231.20
hypothetical protein
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.503715.10
splicing factor TSR1, putative
— Both
TcCLB.504055.60
hypothetical protein, conserved
— Both
TcCLB.507529.10
Cell growth-regulating nucleolar protein, put
— Both
TcCLB.511107.41 ⚠
ATP-dependent Clp protease subunit heat shock
— Both
TcCLB.507099.120
hypothetical protein, conserved
— Both
TcCLB.510325.10 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcCLB.508185.19 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcCLB.511423.160
RWD domain-containing protein
— Both
TcCLB.506829.10
Dyggve-Melchior-Clausen syndrome protein, put
— Both
TcCLB.505807.180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TcCLB.511127.110 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
TcCLB.511529.9 ⚠
Importin-beta N-terminal domain/HEAT-like rep
— Both
TcCLB.504019.9 ⚠
Importin-beta N-terminal domain/HEAT-like rep
— Both
TcCLB.509205.120 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.