TcCLB.511127.110

ATP-dependent protease ATPase subunit HslU2
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_137689 OG7: OG7_0004131 151 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 151 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506739.50 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
TcCLB.503653.30 ⚠
ribosomal RNA processing protein 41B, putativ
— OG7
TcCLB.510963.30 ⚠
cap guanine-N7 methyltransferase
— OG7
TcCLB.506375.60 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.506733.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.506375.10 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510149.120 ⚠
flagellar radial spoke protein-like, putative
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508777.100 ⚠
cyclin 1
— OG7
TcCLB.509965.380 ⚠
dTDP-glucose 4,6-dehydratase, putative
— OG7
TcCLB.510105.200 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.504153.180 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG7
TcCLB.506249.20 ⚠
protein transport protein Sec23A, putative
— OG7
TcCLB.503677.10 ⚠
phosphomannose isomerase, putative
— OG7
TcCLB.506677.39 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
TcCLB.506359.60 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— OG7
TcCLB.509965.370 ⚠
adenosine kinase, putative
— OG7
TcCLB.508277.140 ⚠
phosphomevalonate kinase protein, putative
— OG7
TcCLB.510997.40 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG7
TcCLB.511911.130 ⚠
phosphoglucomutase
— OG7
TcCLB.509805.20 ⚠
cAMP phosphodiesterase A, putative
— OG7
TcCLB.504029.101 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506411.10 ⚠
metallo-peptidase, clan MA(E), family M3, put
— OG7
TcCLB.510105.20 ⚠
Ribosomal RNA processing protein 41A
— OG7
TcCLB.509205.110 ⚠
elongation factor G2-like protein, putative
— OG7
TcCLB.507709.44 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.511313.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511353.4 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511351.41 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.507841.34 ⚠
exosome-associated protein 4, putative
— OG7
TcCLB.511575.100 ⚠
protein transport protein SEC23, putative
— OG7
TcCLB.511871.30 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— OG7
TcCLB.506963.110 ⚠
NUDIX hydrolase 3, putative
— OG7
TcCLB.510141.10 ⚠
thymine-7-hydroxylase, putative
— OG7
TcCLB.511575.60 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.509099.59 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.