TcCLB.508777.100

cyclin 1
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_127800 OG7: OG7_0020578 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507011.30 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcCLB.506357.50
alcohol dehydrogenase, putative
— Both
TcCLB.510091.50
chaperone protein DnaJ, putative
— Both
TcCLB.506359.60
UTP-glucose-1-phosphate uridylyltransferase 2
— Both
TcCLB.506165.10
hypothetical protein, conserved
— Both
TcCLB.510141.10 ⚠
thymine-7-hydroxylase, putative
— OG7
TcCLB.511303.40 ⚠
carnitine O-acetyltransferase, putative
— OG7
TcCLB.507211.10 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511353.4 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511351.41 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.506249.20 ⚠
protein transport protein Sec23A, putative
— OG7
TcCLB.509205.110 ⚠
elongation factor G2-like protein, putative
— OG7
TcCLB.509199.10 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
TcCLB.511751.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507509.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507993.150
Activator of Hsp90 ATPase, N-terminal/Activat
— Both
TcCLB.503675.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.506411.10 ⚠
metallo-peptidase, clan MA(E), family M3, put
— OG7
TcCLB.511127.110 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG7
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506625.140 ⚠
methyltransferase domain containing protein,
— OG7
TcCLB.506693.4
eukaryotic translation initiation factor 2 su
— Both
TcCLB.506925.319 ⚠
isocitrate dehydrogenase, putative
— Both
TcCLB.511575.100 ⚠
protein transport protein SEC23, putative
— Both
TcCLB.507507.49 ⚠
hypothetical protein, conserved
— Both
TcCLB.506677.39 ⚠
Elongation factor G1, mitochondrial, putative
— Both
TcCLB.508277.140
phosphomevalonate kinase protein, putative
— Both
TcCLB.506963.110
NUDIX hydrolase 3, putative
— Both
TcCLB.511425.10 ⚠
serine/threonine protein phosphatase 2A regul
— Both
TcCLB.511575.60 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TcCLB.503803.4 ⚠
serine/threonine protein phosphatase 2A regul
— Both
TcCLB.510293.20 ⚠
cytosolic factor SEC14, putative, phosphatidy
— Both
TcCLB.508389.10 ⚠
methyltransferase domain containing protein,
— Both
TcCLB.504153.180
UDP-N-acetylglucosamine pyrophosphorylase, pu
— Both
TcCLB.506739.50 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
TcCLB.508347.130
deoxyhypusine hydroxylase, putative
— Both
TcCLB.511911.130
phosphoglucomutase
— Both
TcCLB.510997.40
enoyl-CoA hydratase/isomerase family protein,
— Both
TcCLB.503677.10
phosphomannose isomerase, putative
— Both
TcCLB.505807.180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TcCLB.505987.50 ⚠
adenosine kinase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.