TcCLB.506739.50

ATP-dependent protease ATPase subunit HslU1, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_106348 OG7: OG7_0004131 144 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 144 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511127.110 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
TcCLB.509965.370 ⚠
adenosine kinase, putative
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508095.20 ⚠
mRNA cap methyltransferase-like protein, puta
— OG7
TcCLB.511107.41 ⚠
ATP-dependent Clp protease subunit heat shock
— OG7
TcCLB.510963.30 ⚠
cap guanine-N7 methyltransferase
— OG7
TcCLB.506375.60 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.507529.10 ⚠
Cell growth-regulating nucleolar protein, put
— OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.504055.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506733.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507099.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— OG7
TcCLB.504153.360 ⚠
succinyl-coA:3-ketoacid-coenzyme A transferas
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.511745.10 ⚠
heat shock 70 kDa protein, mitochondrial prec
— OG7
TcCLB.506375.10 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504089.50 ⚠
Flagellar radial spoke protein 4/6
— OG7
TcCLB.510149.120 ⚠
flagellar radial spoke protein-like, putative
— OG7
TcCLB.504625.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcCLB.508271.10 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.509967.40 ⚠
Aminoacyl-tRNA editing domain containing prot
— OG7
TcCLB.508277.100 ⚠
cAMP specific phosphodiesterase, putative
— OG7
TcCLB.511313.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.505987.50 ⚠
adenosine kinase, putative
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.511353.4 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511351.41 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.507841.34 ⚠
exosome-associated protein 4, putative
— OG7
TcCLB.503897.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510141.10 ⚠
thymine-7-hydroxylase, putative
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.506693.4 ⚠
eukaryotic translation initiation factor 2 su
— OG7
TcCLB.506859.70 ⚠
guide RNA associated protein, GAP2, putative
— OG7
TcCLB.413977.10 ⚠
guide RNA associated protein, GAP1, putative
— OG7
TcCLB.506829.10 ⚠
Dyggve-Melchior-Clausen syndrome protein, put
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.