TcCLB.511745.10

heat shock 70 kDa protein, mitochondrial precursor, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100423 OG7: OG7_0000776 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.508813.15 ⚠
heat shock protein 70, putative (fragment)
— +2 more OG6
TcCLB.509543.50 ⚠
DNAK protein, putative
— +2 more OG6
TcCLB.511211.170 ⚠
heat shock protein 70 (hsp70), putative
— +2 more OG6
TcCLB.511211.220 ⚠
heat shock protein 70, putative
— +2 more OG6
TcCLB.511211.160 ⚠
heat shock protein 70 (hsp70), putative
— +2 more OG6
TcCLB.506135.9 ⚠
heat shock 70 kDa protein, putative (fragment
— +2 more OG6
TcCLB.511107.41 ⚠
ATP-dependent Clp protease subunit heat shock
— Both
TcCLB.418069.10 ⚠
heat shock protein 70 (hsp70), putative (frag
— +2 more OG6
TcCLB.508807.10 ⚠
atp-dependent chaperone, ATP-dependent Clp pr
— Both
TcCLB.509125.20 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.509157.279 ⚠
Chaperonin HSP60, mitochondrial
— Both
TcCLB.503479.49 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcCLB.504625.80 ⚠
hypothetical protein, conserved
— Both
TcCLB.508209.100 ⚠
10 kDa heat shock protein, putative
— Both
TcCLB.511393.88 ⚠
hypothetical protein, conserved (fragment)
— Both
TcCLB.508209.120 ⚠
10 kDa heat shock protein, putative
— Both
TcCLB.508209.90 ⚠
10 kDa heat shock protein, putative
— Both
TcCLB.511395.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.507641.300 ⚠
groELprotein, chaperonin HSP60, mitochondrial
— Both
TcCLB.507641.280 ⚠
chaperonin HSP60, mitochondrial precursor, gr
— Both
TcCLB.507641.290 ⚠
heat shock protein 60, chaperonin HSP60, mito
— Both
TcCLB.507099.120 ⚠
hypothetical protein, conserved
— Both
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.509967.160 ⚠
epsilon tubulin, putative
— OG7
TcCLB.503969.10 ⚠
tubulin delta chain
— OG7
TcCLB.511867.190 ⚠
tubulin gamma chain
— OG7
TcCLB.511707.39 ⚠
Importin subunit beta-4, putative
— OG7
TcCLB.506735.10 ⚠
metallo-peptidase, Clan ME, Family M16, putat
— OG7
TcCLB.511733.130 ⚠
chaperonin HSP60, putative (fragment)
— OG7
TcCLB.511735.10 ⚠
chaperonin HSP60/CNP60, putative
— OG7
TcCLB.510231.20 ⚠
hypothetical protein
— OG7
TcCLB.510963.30 ⚠
cap guanine-N7 methyltransferase
— OG7
TcCLB.506739.50 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TcCLB.506733.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504055.60 ⚠
hypothetical protein, conserved
— Both
TcCLB.507547.30 ⚠
Mitochondrial-processing peptidase subunit al
— Both
TcCLB.511555.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— Both
TcCLB.507929.20 ⚠
co-chaperone GrpE, putative
— Both
TcCLB.506127.150 ⚠
BRO1-like domain/ALIX V-shaped domain binding
— Both
TcCLB.508647.110 ⚠
Archaic Translocase of outer membrane 14 kDa
— Both
TcCLB.504019.9 ⚠
Importin-beta N-terminal domain/HEAT-like rep
— Both
TcCLB.511529.9 ⚠
Importin-beta N-terminal domain/HEAT-like rep
— Both
TcCLB.511127.110 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
TcCLB.508095.20 ⚠
mRNA cap methyltransferase-like protein, puta
— Both
TcCLB.505983.20 ⚠
nucleosome assembly protein-like protein, put
— Both
TcCLB.507963.79 ⚠
nucleosome assembly protein, putative
— Both
TcCLB.510531.30 ⚠
Galactose oxidase, central domain containing
— OG6
TcCLB.506829.10 ⚠
Dyggve-Melchior-Clausen syndrome protein, put
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.