TcCLB.504019.9

Importin-beta N-terminal domain/HEAT-like repeat, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102877 OG7: OG7_0003452 80 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 80 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.468941.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.510165.30 ⚠
R3H domain containing protein, putative
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.503489.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508465.110 ⚠
acyl-CoA dehydrogenase, putative
— OG7
TcCLB.510313.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510181.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506733.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.508469.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503489.10 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcCLB.510105.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.508239.30 ⚠
neurobeachin/beige-like protein, putative
— OG7
TcCLB.510963.30 ⚠
cap guanine-N7 methyltransferase
— OG7
TcCLB.504153.140 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcCLB.504427.250 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.508323.84 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.503479.49 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcCLB.510743.10 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.509267.50 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TcCLB.509669.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510089.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.505807.180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcCLB.509885.60 ⚠
methyltransferase, putative
— OG7
TcCLB.509455.80 ⚠
GTP-binding nuclear protein rtb2, putative
— OG7
TcCLB.508169.9 ⚠
elongation factor 2, putative (fragment)
— OG7
TcCLB.510963.90 ⚠
elongation factor 2, putative
— OG7
TcCLB.508169.20 ⚠
elongation factor 2, putative
— OG7
TcCLB.506211.150 ⚠
polyprenyl synthase, putative
— OG7
TcCLB.504077.40 ⚠
translation elongation factor EF-2, putative
— OG7
TcCLB.511423.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506691.14 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.508469.4 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.508719.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510751.40 ⚠
Importin 1 (fragment)
— OG7
TcCLB.510879.40 ⚠
Carboxypeptidase-like protein
— OG7
TcCLB.510741.229 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.507639.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— Both
TcCLB.511113.9 ⚠
hypothetical protein, conserved (fragment)
— Both
TcCLB.507047.80 ⚠
zinc-finger protein ZPR1, putative
— Both
TcCLB.506659.30 ⚠
glutathione synthetase, putative
— Both
TcCLB.510215.10 ⚠
NADH-dependent fumarate reductase, putative
— Both
TcCLB.509125.20 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
TcCLB.506941.280 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TcCLB.507797.9 ⚠
nuclear transcription factor, putative
— Both
TcCLB.508807.10 ⚠
atp-dependent chaperone, ATP-dependent Clp pr
— Both
TcCLB.504137.10 ⚠
isoleucyl-tRNA synthetase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.