TcCLB.510105.9

ATP-dependent DEAD/H RNA helicase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100340 OG7: OG7_0002665 127 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 127 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506529.590 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcCLB.510861.14 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.506249.20 ⚠
protein transport protein Sec23A, putative
— OG7
TcCLB.511741.30 ⚠
replication factor C, subunit 2, putative
— OG7
TcCLB.508647.40 ⚠
replication factor C, subunit 1, putative
— OG7
TcCLB.511067.10 ⚠
tubulin folding cofactor D, putative
— OG7
TcCLB.507527.20 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcCLB.511589.160 ⚠
replication factor C, subunit 4, putative
— OG7
TcCLB.510737.110 ⚠
replication factor C, subunit 3, putative
— OG7
TcCLB.510101.250 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504153.140 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcCLB.508465.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506755.279 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504935.10 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.506375.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcCLB.506127.170 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcCLB.509805.130 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.504427.50 ⚠
5'-AMP-activated protein kinase subunit beta,
— OG7
TcCLB.508921.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510101.210 ⚠
PUB domain containing protein, putative
— OG7
TcCLB.507809.110 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.510859.50 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.421959.10 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.508183.4 ⚠
aspartyl aminopeptidase, putative (fragment)
— OG7
TcCLB.506457.130 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TcCLB.508271.10 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcCLB.503489.10 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcCLB.413977.10 ⚠
guide RNA associated protein, GAP1, putative
— OG7
TcCLB.511353.40 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcCLB.506779.50 ⚠
proteasome beta 3 subunit, putative
— OG7
TcCLB.506775.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511621.180 ⚠
Phosducin, putative
— OG7
TcCLB.509069.20 ⚠
ATP binding protein-like protein, putative
— OG7
TcCLB.509153.110 ⚠
hypothetical protein
— OG7
TcCLB.504057.110 ⚠
exosome complex exonuclease, putative, riboso
— OG7
TcCLB.510101.200 ⚠
zinc finger ccch and cchc domain-containing p
— OG7
TcCLB.509597.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509803.40 ⚠
5-oxoprolinase, putative
— OG7
TcCLB.506885.380 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511351.9 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— OG7
TcCLB.510879.40 ⚠
Carboxypeptidase-like protein
— OG7
TcCLB.511111.10 ⚠
translation initiation factor IF-2, putative
— OG7
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.507537.30 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
TcCLB.507747.220 ⚠
protein farnesyltransferase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.