TcCLB.511067.10

tubulin folding cofactor D, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102599 OG7: OG7_0006853 181 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 181 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcCLB.511421.110 ⚠
developmentally regulated phosphoprotein, put
— Both
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.507809.110
WD domain, G-beta repeat, putative
— Both
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— Both
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcCLB.509805.130
bifunctional aminoacyl-tRNA synthetase, putat
— +2 more Both
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
TcCLB.508271.10 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
TcCLB.506183.9 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.507537.30 ⚠
cysteinyl-tRNA synthetase, putative
— Both
TcCLB.506531.60 ⚠
hypothetical protein, conserved
— Both
TcCLB.506529.590 ⚠
Centrosomal protein of 164 kDa, putative
— Both
TcCLB.427247.10 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcCLB.508539.30
hypothetical protein, conserved
— Both
TcCLB.507993.280 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— Both
TcCLB.507841.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510349.30
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
TcCLB.506127.170 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.510737.110 ⚠
replication factor C, subunit 3, putative
— OG7
TcCLB.511589.160 ⚠
replication factor C, subunit 4, putative
— OG7
TcCLB.511741.30 ⚠
replication factor C, subunit 2, putative
— OG7
TcCLB.506517.100 ⚠
ATPase family associated with various cellula
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.509007.20
hypothetical protein, conserved
— Both
TcCLB.503841.80 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
TcCLB.506859.70
guide RNA associated protein, GAP2, putative
— Both
TcCLB.509803.40
5-oxoprolinase, putative
— Both
TcCLB.511001.190
vacuolar ATP synthase subunit d, putative
— Both
TcCLB.503589.10
GDP-mannose pyrophosphorylase
— Both
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcCLB.503855.40 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
TcCLB.506625.60 ⚠
inositol 5-phosphatase 1, putative
— Both
TcCLB.509805.210
hypothetical protein, conserved
— Both
TcCLB.508569.130 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TcCLB.508717.40
branch point binding protein, putative
— Both
TcCLB.511545.140 ⚠
hypothetical protein, conserved
— OG6
TcCLB.511585.40
DNA-damage inducible protein DDI1-like protei
— Both
TcCLB.509543.50 ⚠
DNAK protein, putative
— OG6
TcCLB.511731.80
Mitochondrial small ribosomal subunit mS56, p
— Both
TcCLB.506773.20
hypothetical protein, conserved
— Both
TcCLB.508207.230 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TcCLB.508813.15 ⚠
heat shock protein 70, putative (fragment)
— OG6
TcCLB.508535.10 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
TcCLB.511211.170 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.511571.40
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.