TcCLB.507875.10

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_158396 OG7: OG7_0000785 295 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 295 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510101.250 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506215.19 ⚠
intraflagellar transport protein 140, putativ
— OG7
TcCLB.508647.210 ⚠
dynein arm light chain, putative
— OG7
TcCLB.509967.170 ⚠
dynein arm light chain, putative
— OG7
TcCLB.504009.40 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcCLB.511585.130 ⚠
ubiquitin activating enzyme, putative
— OG7
TcCLB.506503.110 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
TcCLB.506859.70 ⚠
guide RNA associated protein, GAP2, putative
— OG7
TcCLB.510243.50 ⚠
UMP/CMP kinase, putative
— OG7
TcCLB.416883.18 ⚠
proteasome alpha 2 subunit, putative
— OG7
TcCLB.503479.30 ⚠
adenylate kinase 1
— OG7
TcCLB.506947.90 ⚠
adenylate kinase, putative
— OG7
TcCLB.508837.180 ⚠
DNA polymerase I alpha catalytic subunit, put
— OG7
TcCLB.510259.6 ⚠
DNA polymerase delta catalytic subunit, putat
— OG7
TcCLB.509769.130 ⚠
DNA polymerase zeta catalytic subunit, putati
— OG7
TcCLB.511145.43 ⚠
proteasome subunit alpha type-5, putative
— OG7
TcCLB.506167.40 ⚠
proteasome subunit alpha type-1, putative
— OG7
TcCLB.504213.120 ⚠
proteasome alpha 3 subunit, putative
— OG7
TcCLB.511867.50 ⚠
proteasome alpha 7 subunit, putative
— OG7
TcCLB.506885.350 ⚠
proteasome alpha 1 subunit, putative
— OG7
TcCLB.503613.20 ⚠
proteasome alpha 7 subunit, putative
— OG7
TcCLB.506211.40 ⚠
intraflagellar transport protein 52
— OG7
TcCLB.509625.10 ⚠
ATP-dependent RNA helicase, putative (fragmen
— OG7
TcCLB.511315.9 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.506179.59 ⚠
ATP-dependent RNA helicase, putative (fragmen
— OG7
TcCLB.509769.70 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcCLB.504051.20 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcCLB.511313.40 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.506457.130 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TcCLB.503595.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509497.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510091.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507805.9 ⚠
histone deacetylase 4, putative
— OG7
TcCLB.507803.49 ⚠
histone deacetylase, putative
— OG7
TcCLB.503653.50 ⚠
histone deacetylase, putative
— OG7
TcCLB.507809.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506181.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504159.80 ⚠
histone deacetylase, putative
— OG7
TcCLB.503897.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— OG7
TcCLB.508489.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507929.20 ⚠
co-chaperone GrpE, putative
— OG7
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.510431.250 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.506607.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.507809.30 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
TcCLB.509805.210 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507511.10 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcCLB.509803.40 ⚠
5-oxoprolinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.