TcCLB.506947.90

adenylate kinase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_104102 OG7: OG7_0001354 129 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 129 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510755.19 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507809.30 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
TcCLB.506685.30 ⚠
thymidylate kinase, putative
— Both
TcCLB.508781.120 ⚠
hypothetical protein, conserved
— Both
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— Both
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— Both
TcCLB.506357.130 ⚠
hypothetical protein, conserved
— Both
TcCLB.509599.40 ⚠
hypothetical protein, conserved
— Both
TcCLB.511313.30 ⚠
formin, putative
— OG7
TcCLB.506203.80 ⚠
formin-like protein
— OG7
TcCLB.511393.30 ⚠
formin homology 2 (FH2) domain protein, putat
— OG7
TcCLB.504883.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.506607.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.510431.250 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.508771.20 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.509099.50 ⚠
trypanothione synthetase
— OG7
TcCLB.508771.10 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.486465.9 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.504427.10 ⚠
trypanothione synthetase, putative
— OG7
TcCLB.503897.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504159.80 ⚠
histone deacetylase, putative
— OG7
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcCLB.504119.4 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcCLB.504051.20 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcCLB.509769.70 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.507641.14 ⚠
neurobeachin/beige protein, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509951.49 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcCLB.509151.80 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG7
TcCLB.507011.60 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcCLB.508779.90 ⚠
structural maintenance of chromosome protein
— OG7
TcCLB.508357.40 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TcCLB.509073.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.511115.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511075.40 ⚠
cullin, putative
— OG7
TcCLB.511417.40 ⚠
DNA-directed RNA polymerase III, putative
— OG7
TcCLB.507639.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.510753.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510101.150 ⚠
adaptin-related protein-like, putative
— OG7
TcCLB.503637.20 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.