TcCLB.509073.30

ubiquitin hydrolase, putative, cysteine peptidase, Clan CA, family C19, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_146381 OG7: OG7_0001214 178 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 178 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504867.20 ⚠
ABC transporter, putative
— Both
TcCLB.504427.140 ⚠
hypothetical protein, conserved
— Both
TcCLB.506357.130 ⚠
hypothetical protein, conserved
— +1 more Both
TcCLB.510431.250 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.506673.60 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.511215.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506227.80 ⚠
mitochondrial DNA polymerase I protein B, put
— OG7
TcCLB.507629.30 ⚠
Dpy-30 motif containing protein, putative
— OG7
TcCLB.509155.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.508389.10 ⚠
methyltransferase domain containing protein,
— OG7
TcCLB.506625.140 ⚠
methyltransferase domain containing protein,
— OG7
TcCLB.505943.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.505941.49 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506829.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506265.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.486901.10 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TcCLB.510091.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511585.130 ⚠
ubiquitin activating enzyme, putative
— OG7
TcCLB.509153.100 ⚠
protein arginine n-methyltransferase 7
— OG7
TcCLB.510311.140 ⚠
arginine N-methyltransferase, putative
— OG7
TcCLB.506947.80 ⚠
arginine N-methyltransferase, type I
— OG7
TcCLB.503811.10 ⚠
heat shock protein 90, putative
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.506591.4 ⚠
heat shock protein 90, putative
— OG7
TcCLB.504153.310 ⚠
heat shock protein, putative
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506147.30 ⚠
synaptojanin (N-terminal domain), putative, i
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.510295.40 ⚠
Protein C21orf2 homolog, putative
— OG7
TcCLB.510737.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.504159.80 ⚠
histone deacetylase, putative
— OG7
TcCLB.507809.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503653.50 ⚠
histone deacetylase, putative
— OG7
TcCLB.507803.49 ⚠
histone deacetylase, putative
— OG7
TcCLB.507805.9 ⚠
histone deacetylase 4, putative
— OG7
TcCLB.503595.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508647.170 ⚠
DNA polymerase theta
— OG7
TcCLB.506265.30 ⚠
mitochondrial DNA polymerase I protein A, put
— OG7
TcCLB.506775.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504179.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506947.90 ⚠
adenylate kinase, putative
— OG7
TcCLB.507093.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509625.10 ⚠
ATP-dependent RNA helicase, putative (fragmen
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.