TcCLB.506265.30

mitochondrial DNA polymerase I protein A, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101669 OG7: OG7_0003628 42 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 42 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.508389.10 ⚠
methyltransferase domain containing protein,
— OG7
TcCLB.508207.100 ⚠
60S ribosomal protein L7, putative
— OG6
TcCLB.508207.110 ⚠
60S ribosomal protein L7, putative
— OG6
TcCLB.510879.110 ⚠
ribosomal protein L3, putative
— OG6
TcCLB.510879.120 ⚠
ribosomal protein L3, putative
— OG6
TcCLB.508719.50 ⚠
hypothetical protein, conserved
— OG6
TcCLB.510241.50 ⚠
60S ribosomal protein L10, putative
— OG6
TcCLB.510243.40 ⚠
60S ribosomal protein L10, putative
— OG6
TcCLB.508719.30 ⚠
hypothetical protein, conserved
— OG6
TcCLB.507603.30 ⚠
PITH domain-containing protein
— OG7
TcCLB.511215.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506945.290 ⚠
ribosomal protein L15, putative
— OG6
TcCLB.506625.140 ⚠
methyltransferase domain containing protein,
— OG7
TcCLB.509073.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.511799.9 ⚠
Nucleolar protein 136, putative
— OG7
TcCLB.466879.10 ⚠
AARP2CN (NUC121) domain/Protein of unknown fu
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TcCLB.506931.10 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
TcCLB.508357.40 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.507077.9 ⚠
Nucleolar protein 136, putative
— OG7
TcCLB.506525.10 ⚠
nuclear segregation protein, putative
— OG6
TcCLB.506401.320 ⚠
60S ribosomal protein L7a, putative
— OG6
TcCLB.506401.180 ⚠
eukaryotic translation initiation factor 3 su
— OG6
TcCLB.510351.70 ⚠
hypothetical protein, conserved
— OG6
TcCLB.509499.10 ⚠
cyclophilin, putative, peptidyl-prolyl cis-tr
— OG6
TcCLB.510259.50 ⚠
21 kDa cyclophilin, putative, PPIase, putativ
— OG6
TcCLB.506925.300 ⚠
cyclophilin a, putative
— OG6
TcCLB.506239.20 ⚠
Metallopeptidase family M24, putative
— OG6
TcCLB.507673.20 ⚠
60S ribosomal protein L13a, putative
— OG6
TcCLB.506739.150 ⚠
60S ribosomal protein L13a, putative
— OG6
TcCLB.510285.80 ⚠
hypothetical protein, conserved
— OG6
TcCLB.510143.5 ⚠
hypothetical protein, conserved (fragment)
— OG6
TcCLB.510741.40 ⚠
hypothetical protein, conserved
— OG6
TcCLB.509149.40 ⚠
60S ribosomal protein L19, putative
— OG6
TcCLB.509149.60 ⚠
60S ribosomal protein L19, putative
— OG6
TcCLB.504103.90 ⚠
PSP1 C-terminal conserved region, putative
— OG6
TcCLB.504181.10 ⚠
60S ribosomal protein L9, putative
— OG6
TcCLB.511729.40 ⚠
60S ribosomal protein L9, putative
— OG6
TcCLB.510323.30 ⚠
60S ribosomal protein L13, putative
— OG6
TcCLB.509151.140 ⚠
60S ribosomal protein L23a, putative
— OG6
TcCLB.510767.10 ⚠
ribosomal protein L15, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.