TcCLB.506525.10

nuclear segregation protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_144434 OG7: OG7_0034038 67 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 67 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510879.120 ⚠
ribosomal protein L3, putative
— Both
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.506945.70 ⚠
protein mkt1, putative
— Both
TcCLB.510101.350
hypothetical protein, conserved
— Both
TcCLB.508719.30
hypothetical protein, conserved
— Both
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— Both
TcCLB.508719.50
hypothetical protein, conserved
— Both
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.510879.110 ⚠
ribosomal protein L3, putative
— Both
TcCLB.503975.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.503975.70
hypothetical protein, conserved
— Both
TcCLB.507711.160
hypothetical protein, conserved
— Both
TcCLB.510431.170
hypothetical protein, conserved
— Both
TcCLB.507511.40
G5-interacting protein, putative
— Both
TcCLB.509967.40
Aminoacyl-tRNA editing domain containing prot
— Both
TcCLB.506287.150 ⚠
GTP-binding protein, putative
— OG7
TcCLB.503905.50 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcCLB.508541.190 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
TcCLB.506239.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507611.270 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506777.50 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
TcCLB.506223.40 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcCLB.510609.30 ⚠
GTPase, putative
— OG7
TcCLB.507993.130 ⚠
60S ribosomal protein L7, putative
— OG7
TcCLB.506945.290 ⚠
ribosomal protein L15, putative
— Both
TcCLB.504153.300 ⚠
GTPase protein, putative
— OG7
TcCLB.506211.200 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
TcCLB.506465.30
hypothetical protein, conserved
— OG7
TcCLB.504133.45 ⚠
Temperature dependent protein affecting M2 ds
— OG7
TcCLB.510055.70
Kinetochore interacting protein 5, putative
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.503975.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510143.5
hypothetical protein, conserved (fragment)
— Both
TcCLB.509149.40 ⚠
60S ribosomal protein L19, putative
— Both
TcCLB.510241.50 ⚠
60S ribosomal protein L10, putative
— Both
TcCLB.506925.300 ⚠
cyclophilin a, putative
— OG6
TcCLB.510351.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.506401.180
eukaryotic translation initiation factor 3 su
— Both
TcCLB.506401.320
60S ribosomal protein L7a, putative
— Both
TcCLB.510259.50 ⚠
21 kDa cyclophilin, putative, PPIase, putativ
— OG6
TcCLB.509499.10 ⚠
cyclophilin, putative, peptidyl-prolyl cis-tr
— OG6
TcCLB.508207.100 ⚠
60S ribosomal protein L7, putative
— Both
TcCLB.510105.50 ⚠
fibrillarin, putative
— Both
TcCLB.506739.150 ⚠
60S ribosomal protein L13a, putative
— Both
TcCLB.506211.250 ⚠
fibrillarin, putative
— Both
TcCLB.507673.20 ⚠
60S ribosomal protein L13a, putative
— Both
TcCLB.506239.20 ⚠
Metallopeptidase family M24, putative
— Both
TcCLB.509445.39 ⚠
glutamate dehydrogenase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.