TcCLB.504133.45

Temperature dependent protein affecting M2 dsRNA replication, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_143822 OG7: OG7_0013037 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511409.10 ⚠
PAB1-binding protein , putative
— OG7
TcCLB.507831.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506931.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506829.50 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG7
TcCLB.510101.350 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509445.39 ⚠
glutamate dehydrogenase, putative
— OG7
TcCLB.505843.10 ⚠
glutamate dehydrogenase, putative
— OG7
TcCLB.508989.90 ⚠
Eukaryotic translation initiation factor 4 ga
— OG7
TcCLB.507483.60 ⚠
translation-associated element 2, putative
— OG7
TcCLB.509967.40 ⚠
Aminoacyl-tRNA editing domain containing prot
— OG7
TcCLB.507831.40 ⚠
Zinc finger CCCH domain-containing protein 35
— OG7
TcCLB.503455.30 ⚠
Protein of unknown function (DUF3648), putati
— OG7
TcCLB.507831.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509805.230 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503579.30 ⚠
DNA polymerase sigma-like protein, putative
— OG7
TcCLB.509297.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506525.10 ⚠
nuclear segregation protein, putative
— OG7
TcCLB.507143.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503953.50 ⚠
Beta-lactamase superfamily domain containing
— OG7
TcCLB.506755.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506755.200 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.449247.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503959.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510029.40 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
TcCLB.511801.10 ⚠
leucine rich repeat
— OG7
TcCLB.507669.14 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507011.250 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
TcCLB.503525.20 ⚠
Cyclin 12, L-type
— OG7
TcCLB.510181.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508727.44 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503975.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506513.150 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.508205.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506779.60 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— OG7
TcCLB.504171.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511211.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507521.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509231.39 ⚠
zinc finger protein 3
— OG7
TcCLB.506739.99 ⚠
zinc finger (CCCH type) protein, putative
— OG7
TcCLB.506945.210 ⚠
Zinc finger CCCH domain-containing protein 47
— OG7
TcCLB.504929.5 ⚠
zinc finger CCCH domain containing protein 11
— OG7
TcCLB.482369.10 ⚠
protein phosphatase 2A regulatory subunit, pu
— OG7
TcCLB.508209.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.397937.10 ⚠
pumilio/PUF RNA binding protein 1, putative
— OG7
TcCLB.509965.40 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.504125.30 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.506747.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506941.260 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.