TcCLB.508277.360

ubiquitin hydrolase, putative, cysteine peptidase, Clan CA, family C19, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_145141 OG7: OG7_0002166 233 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 233 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504867.20 ⚠
ABC transporter, putative
— Both
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.506625.80 ⚠
cAMP-specific phosphodiesterase, putative
— Both
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.510743.10 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.504427.250 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.510741.229 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.504137.80 ⚠
adenylyl cyclase-associated protein, putative
— OG7
TcCLB.506755.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506755.200 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511801.20 ⚠
D123, putative
— OG7
TcCLB.506945.50 ⚠
T-complex protein 11, putative
— OG7
TcCLB.510601.30 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcCLB.506367.20 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcCLB.506743.220 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506745.4 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.510737.100 ⚠
Peroxin 19
— OG7
TcCLB.510749.4 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.503455.30 ⚠
Protein of unknown function (DUF3648), putati
— OG7
TcCLB.507993.369 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
TcCLB.510757.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.509965.40 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.510055.70 ⚠
Kinetochore interacting protein 5, putative
— OG7
TcCLB.510747.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506465.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506513.150 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.510101.490 ⚠
anion-transporting ATPase-like, putative
— OG7
TcCLB.505945.20 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.505945.30 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.506375.70 ⚠
Fungal tRNA ligase phosphodiesterase domain c
— OG7
TcCLB.510231.20 ⚠
hypothetical protein
— OG7
TcCLB.509167.100 ⚠
valyl-tRNA synthetase, putative
— OG7
TcCLB.506885.416 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504147.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508727.44 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503975.40 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.