TcCLB.509127.110

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_115523 OG7: OG7_0001150 359 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 359 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— OG7
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.507929.20 ⚠
co-chaperone GrpE, putative
— OG7
TcCLB.504867.20 ⚠
ABC transporter, putative
— OG7
TcCLB.480785.10 ⚠
serine/threonine kinase, putative, CMGC/DYRK
— OG7
TcCLB.508717.40 ⚠
branch point binding protein, putative
— OG7
TcCLB.507809.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508569.130 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.509103.4 ⚠
protein kinase, putative
— OG7
TcCLB.509805.210 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506519.60 ⚠
CMGC/CLK family protein kinase, putative
— OG7
TcCLB.506699.3 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.506223.80 ⚠
Metalloprotease M41 FtsH, putative
— OG7
TcCLB.506223.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510997.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510143.24 ⚠
Hsc70-interacting protein (Hip), putative
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.509757.20 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcCLB.511573.20 ⚠
hypothetical protein
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.510105.210 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.503677.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510769.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510143.40 ⚠
UBX domain-containing protein
— OG7
TcCLB.508387.30 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.508723.80 ⚠
disgorgin, putative
— OG7
TcCLB.508781.20 ⚠
ATP synthase, putative
— OG7
TcCLB.508465.110 ⚠
acyl-CoA dehydrogenase, putative
— OG7
TcCLB.506811.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506025.50 ⚠
Vacuolar proton pump subunit B, putative
— OG7
TcCLB.506405.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506925.319 ⚠
isocitrate dehydrogenase, putative
— OG7
TcCLB.506495.3 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507925.69 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506739.190 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcCLB.506869.60 ⚠
protein kinase PK4, putative
— OG7
TcCLB.506473.10 ⚠
Pre-mRNA-splicing factor 38, putative
— OG7
TcCLB.504203.50 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.506513.50 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcCLB.508181.20 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcCLB.508781.110 ⚠
2-oxoisovalerate dehydrogenase alpha subunit,
— OG7
TcCLB.507907.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510213.110 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TcCLB.504881.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506635.60 ⚠
pyroglutamyl-peptidase I, putative
— OG7
TcCLB.511751.180 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcCLB.504507.5 ⚠
trypanothione reductase, putative (fragment)
— OG7
TcCLB.511211.220 ⚠
heat shock protein 70, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.