TcCLB.509757.20

leucine carboxyl methyltransferase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100931 OG7: OG7_0005126 91 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 91 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507711.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510963.50 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcCLB.508181.20 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcCLB.508569.130 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.508207.230 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.508813.50 ⚠
oxidoreductase-like protein, putative
— OG7
TcCLB.507011.250 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506773.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506859.70 ⚠
guide RNA associated protein, GAP2, putative
— OG7
TcCLB.508539.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511801.10 ⚠
leucine rich repeat
— OG7
TcCLB.510963.39 ⚠
PUB domain containing protein, putative
— OG7
TcCLB.507669.14 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.508307.150 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503525.20 ⚠
Cyclin 12, L-type
— OG7
TcCLB.449247.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508205.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504171.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511555.60 ⚠
ubiquitin ligase, putative
— OG7
TcCLB.508535.10 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TcCLB.511571.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506405.120 ⚠
V-type ATPase, A subunit, putative
— OG7
TcCLB.506503.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506933.60 ⚠
mitochondrial RNA binding protein, putative
— OG7
TcCLB.509007.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511211.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509007.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508717.40 ⚠
branch point binding protein, putative
— OG7
TcCLB.511067.10 ⚠
tubulin folding cofactor D, putative
— OG7
TcCLB.509827.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507521.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511731.80 ⚠
Mitochondrial small ribosomal subunit mS56, p
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506025.50 ⚠
Vacuolar proton pump subunit B, putative
— OG7
TcCLB.507099.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508515.30 ⚠
RNA-binding protein 38, putative
— OG7
TcCLB.509769.30 ⚠
Inositol hexakisphosphate, putative
— OG7
TcCLB.503405.10 ⚠
glutamine synthetase
— OG7
TcCLB.511211.220 ⚠
heat shock protein 70, putative
— OG7
TcCLB.511585.40 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TcCLB.509805.210 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.