TcCLB.510431.220

ribosome assembly protein RRB1, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102504 OG7: OG7_0007856 225 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 225 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509777.100 ⚠
ubiquitin-activating enzyme, putative
— Both
TcCLB.507809.110 ⚠
WD domain, G-beta repeat, putative
— Both
TcCLB.509805.130 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
TcCLB.503579.110 ⚠
pseudouridylate synthase I, putative
— OG7
TcCLB.511585.130 ⚠
ubiquitin activating enzyme, putative
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.509805.210 ⚠
hypothetical protein, conserved
— Both
TcCLB.511751.180 ⚠
pseudouridine synthase A-like protein, putati
— Both
TcCLB.506859.70 ⚠
guide RNA associated protein, GAP2, putative
— Both
TcCLB.508277.190 ⚠
ERAD-associated E3 ubiquitin-protein ligase H
— OG7
TcCLB.508387.30 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.504153.310 ⚠
heat shock protein, putative
— OG7
TcCLB.506591.4 ⚠
heat shock protein 90, putative
— OG7
TcCLB.506739.190 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcCLB.503811.10 ⚠
heat shock protein 90, putative
— OG7
TcCLB.504203.50 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.480785.10 ⚠
serine/threonine kinase, putative, CMGC/DYRK
— OG7
TcCLB.503893.140 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.506673.60 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcCLB.506363.90 ⚠
amidohydrolase, putative
— Both
TcCLB.510431.270 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510431.140 ⚠
dual specificity tyrosine-phosphorylation-reg
— OG7
TcCLB.486901.10 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TcCLB.506265.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507929.20 ⚠
co-chaperone GrpE, putative
— OG7
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.510737.110 ⚠
replication factor C, subunit 3, putative
— OG7
TcCLB.511589.160 ⚠
replication factor C, subunit 4, putative
— OG7
TcCLB.511741.30 ⚠
replication factor C, subunit 2, putative
— OG7
TcCLB.506517.100 ⚠
ATPase family associated with various cellula
— OG7
TcCLB.510963.50 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.506513.24 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.510073.30 ⚠
pumilio/PUF RNA binding protein 4, putative
— OG7
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— Both
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcCLB.511001.190 ⚠
vacuolar ATP synthase subunit d, putative
— Both
TcCLB.506895.40 ⚠
Kinesin-13 1, putative
— OG7
TcCLB.504153.140 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcCLB.509589.30 ⚠
Kinesin-13 5, putative
— OG7
TcCLB.508921.30 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.505123.28 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.510841.10 ⚠
Kinesin-13 4b, putative (fragment)
— OG7
TcCLB.509597.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.397937.10 ⚠
pumilio/PUF RNA binding protein 1, putative
— OG7
TcCLB.507521.110 ⚠
pumilio/PUF RNA binding protein 5, putative
— OG7
TcCLB.508787.30 ⚠
pumilio/PUF RNA binding protein 3, putative
— OG7
TcCLB.511467.16 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.