TcCLB.503959.50

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101974 OG7: OG7_0002342 155 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 155 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— Both
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.464807.20 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
TcCLB.511467.16 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509767.220 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.511127.250 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508779.40 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.508277.190 ⚠
ERAD-associated E3 ubiquitin-protein ligase H
— OG7
TcCLB.506513.24 ⚠
Ring finger domain containing protein, putati
— OG7
TcCLB.504427.50 ⚠
5'-AMP-activated protein kinase subunit beta,
— OG7
TcCLB.507711.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510431.140 ⚠
dual specificity tyrosine-phosphorylation-reg
— OG7
TcCLB.506941.130 ⚠
SET domain containing protein, putative
— OG7
TcCLB.506341.30 ⚠
beta galactofuranosyl glycosyltransferase, pu
— OG7
TcCLB.508585.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510431.10 ⚠
isopentenyl-diphosphate delta-isomerase (frag
— OG7
TcCLB.510963.50 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcCLB.509581.20 ⚠
beta galactofuranosyl glycosyltransferase, pu
— OG7
TcCLB.503893.140 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.510719.10 ⚠
vacuolar protein sorting-associated protein-l
— OG7
TcCLB.510853.50 ⚠
beta galactofuranosyl glycosyltransferase, pu
— OG7
TcCLB.480785.10 ⚠
serine/threonine kinase, putative, CMGC/DYRK
— OG7
TcCLB.507641.150 ⚠
Ribosomal protein S5, C-terminal domain conta
— OG7
TcCLB.506457.130 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TcCLB.408799.19 ⚠
isopentenyl-diphosphate delta-isomerase (frag
— OG7
TcCLB.504203.50 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.506739.190 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcCLB.507121.40 ⚠
beta galactofuranosyl glycosyltransferase, pu
— OG7
TcCLB.503447.60 ⚠
beta galactofuranosyl glycosyltransferase, pu
— OG7
TcCLB.508387.30 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcCLB.509757.20 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcCLB.506519.60 ⚠
CMGC/CLK family protein kinase, putative
— OG7
TcCLB.508675.9 ⚠
CMGC/DYRK protein kinase, putative (fragment)
— OG7
TcCLB.427247.10 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcCLB.508207.230 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.511427.19 ⚠
conserved protein, unknown function (fragment
— OG7
TcCLB.510609.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508569.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.503487.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510769.70 ⚠
hypothetical protein
— OG7
TcCLB.510747.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504159.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506945.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504147.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510719.74 ⚠
Mitochondrial large ribosomal subunit mL42, p
— OG7
TcCLB.511307.6 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.511729.9 ⚠
calmodulin, putative (fragment)
— OG7
TcCLB.507667.20 ⚠
Mitoribosomal SSU assembly factor 1, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.