TcCLB.511427.19

conserved protein, unknown function (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_173713 OG7: OG7_0063852 75 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 75 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506289.60
Cupin-like domain containing protein, putativ
— Both
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.510741.180 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.508041.60 ⚠
eukaryotic release factor 3, putative
— OG7
TcCLB.503579.110 ⚠
pseudouridylate synthase I, putative
— OG7
TcCLB.508949.4 ⚠
elongation factor 1-alpha (ef-1-alpha), putat
— OG7
TcCLB.508973.50 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
TcCLB.511369.20 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.511369.30 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511369.5 ⚠
elongation factor 1-alpha, putative (fragment
— OG7
TcCLB.506493.50 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
TcCLB.511001.60 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.511801.14 ⚠
protein lipid droplet kinase (LDK)
— OG7
TcCLB.464807.10 ⚠
serine/threonine protein kinase, putative, CA
— OG7
TcCLB.510861.140 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.508241.120 ⚠
rrp44p homologue, putative
— OG7
TcCLB.510257.130 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511733.110 ⚠
GTPase activating protein of Rab-like GTPase,
— OG7
TcCLB.506265.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504203.29 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcCLB.506107.20 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcCLB.417091.10 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcCLB.506135.90 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcCLB.506625.249 ⚠
RNA pseudouridylate synthase protein, putativ
— OG7
TcCLB.506249.20 ⚠
protein transport protein Sec23A, putative
— OG7
TcCLB.511605.30 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.510609.130
hypothetical protein, conserved
— OG7
TcCLB.507811.30 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.511571.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.511709.19
phosphatidylinositol 3-kinase catalytic subun
— OG7
TcCLB.511369.10 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.507841.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.503579.60
hypothetical protein
— Both
TcCLB.506857.50
hypothetical protein, conserved
— Both
TcCLB.507927.40
hypothetical protein, conserved
— Both
TcCLB.509551.140
hypothetical protein, conserved
— Both
TcCLB.464807.20
PA26 p53-induced protein (sestrin), putative
— Both
TcCLB.509801.10
hypothetical protein, conserved
— Both
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— Both
TcCLB.510101.250
hypothetical protein, conserved
— Both
TcCLB.506733.80
hypothetical protein, conserved
— Both
TcCLB.509669.90
XPC-binding domain/UBA/TS-N domain containing
— Both
TcCLB.506135.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.506503.10
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.