TcCLB.508041.60

eukaryotic release factor 3, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101550 OG7: OG7_0001444 115 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 115 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506657.70 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
TcCLB.506885.416 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcCLB.511353.10 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.510231.20 ⚠
hypothetical protein
— OG7
TcCLB.508323.84 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509551.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506375.60 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.506733.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.506375.10 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506289.60 ⚠
Cupin-like domain containing protein, putativ
— OG7
TcCLB.511069.20 ⚠
40S ribosomal protein S8, putative
— OG7
TcCLB.511069.10 ⚠
40S ribosomal protein S8, putative
— OG7
TcCLB.510769.49 ⚠
40S ribosomal protein S6, putative
— OG7
TcCLB.508973.50 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.510741.180 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.511801.60 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
TcCLB.511571.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.507811.30 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.504041.4 ⚠
RNA polymerase I
— OG7
TcCLB.511211.130 ⚠
receptor for activated C kinase 1, putative
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— OG7
TcCLB.508277.180 ⚠
mismatch repair protein MSH3, putative
— OG7
TcCLB.507841.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506135.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.482471.19 ⚠
ATP-dependent RNA helicase SUB2, putative (fr
— OG7
TcCLB.508277.120 ⚠
ribosomal protein S6, putative, NPH2/RS6-like
— OG7
TcCLB.511131.50 ⚠
U4/U6 small nuclear ribonuclear protein, puta
— OG7
TcCLB.511585.190 ⚠
Eukaryotic initiation factor 4A-1
— OG7
TcCLB.508083.10 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcCLB.511139.40 ⚠
ATP-dependent RNA helicase SUB2, putative (fr
— OG7
TcCLB.511753.50 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.511199.9 ⚠
ATP-dependent RNA helicase FAL1, putative (fr
— OG7
TcCLB.511211.120 ⚠
receptor for activated C kinase 1, putative
— OG7
TcCLB.506933.107 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511577.50 ⚠
endo-beta-N-acetylglucosaminidase, putative
— OG7
TcCLB.510769.30 ⚠
U3 small nucleolar RNA-associated protein 6,
— OG7
TcCLB.511427.19 ⚠
conserved protein, unknown function (fragment
— OG7
TcCLB.507483.60 ⚠
translation-associated element 2, putative
— OG7
TcCLB.503579.150 ⚠
RNA editing complex protein MP57, putative, R
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.