TcCLB.503479.70

hook complex protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_389757 OG7: OG7_0007856 208 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 208 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509777.100 ⚠
ubiquitin-activating enzyme, putative
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511751.180 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcCLB.503579.110 ⚠
pseudouridylate synthase I, putative
— OG7
TcCLB.509805.130 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
TcCLB.506859.70 ⚠
guide RNA associated protein, GAP2, putative
— OG7
TcCLB.511585.130 ⚠
ubiquitin activating enzyme, putative
— OG7
TcCLB.509805.210 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507809.110 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.511001.190 ⚠
vacuolar ATP synthase subunit d, putative
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.510101.210 ⚠
PUB domain containing protein, putative
— OG7
TcCLB.464807.20 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506773.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510515.100 ⚠
coronin, putative
— OG7
TcCLB.510609.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511555.80 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
TcCLB.508539.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508271.10 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.506363.70 ⚠
amidohydrolase, putative
— OG7
TcCLB.506363.90 ⚠
amidohydrolase, putative
— OG7
TcCLB.507483.60 ⚠
translation-associated element 2, putative
— OG7
TcCLB.506457.130 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— OG7
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.506733.60 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG7
TcCLB.508973.50 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.510741.180 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.511801.60 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
TcCLB.511571.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.507811.30 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.503479.49 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508357.40 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.511427.19 ⚠
conserved protein, unknown function (fragment
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.