TcCLB.510751.10

poly(A)-specific ribonuclease PARN, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_128943 OG7: OG7_0005534 145 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 145 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.508271.10 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcCLB.507537.30 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
TcCLB.511421.110 ⚠
developmentally regulated phosphoprotein, put
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.506183.9 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
TcCLB.511067.10 ⚠
tubulin folding cofactor D, putative
— OG7
TcCLB.506531.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509803.40 ⚠
5-oxoprolinase, putative
— OG7
TcCLB.511571.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507927.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503811.10 ⚠
heat shock protein 90, putative
— OG7
TcCLB.511181.80 ⚠
threonyl-tRNA synthetase, putative
— OG7
TcCLB.508169.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507993.140 ⚠
RNA-binding protein 29, putative
— OG7
TcCLB.506591.4 ⚠
heat shock protein 90, putative
— OG7
TcCLB.504153.310 ⚠
heat shock protein, putative
— OG7
TcCLB.507713.30 ⚠
heat shock protein 85, putative
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TcCLB.507993.10 ⚠
ATP12 chaperone protein, putative
— OG7
TcCLB.507047.110 ⚠
otubain cysteine peptidase, Clan CA, family C
— OG7
TcCLB.510515.100 ⚠
coronin, putative
— OG7
TcCLB.506147.30 ⚠
synaptojanin (N-terminal domain), putative, i
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.510565.11 ⚠
tyrosine aminotransferase, putative (fragment
— OG7
TcCLB.508537.5 ⚠
tyrosine aminotransferase, putative (fragment
— OG7
TcCLB.510101.150 ⚠
adaptin-related protein-like, putative
— OG7
TcCLB.506625.60 ⚠
inositol 5-phosphatase 1, putative
— OG7
TcCLB.503865.40 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcCLB.508535.50 ⚠
tyrosine aminotransferase
— OG7
TcCLB.503747.10 ⚠
glutamine aminotransferase, putative (fragmen
— OG7
TcCLB.508357.40 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.506673.60 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcCLB.508569.130 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.511585.40 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TcCLB.511001.190 ⚠
vacuolar ATP synthase subunit d, putative
— OG7
TcCLB.510741.220 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510431.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510611.40 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcCLB.510861.14 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.510859.50 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.505965.50 ⚠
phosphonopyruvate decarboxylase, putative
— OG7
TcCLB.506181.40 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
TcCLB.506525.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508927.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506207.40 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.509169.30 ⚠
NUDIX hydrolase domain-like domain-containing
— OG7
TcCLB.510349.30 ⚠
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.