TcCLB.507927.40

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_113914 OG7: OG7_0021257 104 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 104 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510213.110 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
TcCLB.510215.10 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
TcCLB.503467.9 ⚠
NADH-dependent fumarate reductase, putative (
— +2 more Both
TcCLB.503841.80 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
TcCLB.439653.10 ⚠
NADH-dependent fumarate reductase, putative
— OG6
TcCLB.508535.10 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
TcCLB.504153.140
metallo-peptidase, Clan MF, Family M17
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.503885.90
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
TcCLB.511693.10
hypothetical protein
— Both
TcCLB.511067.10
tubulin folding cofactor D, putative
— Both
TcCLB.511427.19
conserved protein, unknown function (fragment
— Both
TcCLB.510525.30
hypothetical protein, conserved
— Both
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.507797.9 ⚠
nuclear transcription factor, putative
— Both
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— Both
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcCLB.507641.14 ⚠
neurobeachin/beige protein, putative
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503579.110 ⚠
pseudouridylate synthase I, putative
— OG7
TcCLB.508239.30 ⚠
neurobeachin/beige-like protein, putative
— OG7
TcCLB.507639.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511709.19
phosphatidylinositol 3-kinase catalytic subun
— OG7
TcCLB.506265.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.486901.10 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TcCLB.504137.60 ⚠
beta adaptin, putative
— OG7
TcCLB.511585.130 ⚠
ubiquitin activating enzyme, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.503811.10 ⚠
heat shock protein 90, putative
— OG7
TcCLB.508569.130 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.506211.150
polyprenyl synthase, putative
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.508323.84 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.511353.10 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcCLB.417091.10 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcCLB.506135.90 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcCLB.506625.249 ⚠
RNA pseudouridylate synthase protein, putativ
— OG7
TcCLB.506249.20 ⚠
protein transport protein Sec23A, putative
— OG7
TcCLB.510609.130
hypothetical protein, conserved
— OG7
TcCLB.510165.30 ⚠
R3H domain containing protein, putative
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.510101.150 ⚠
adaptin-related protein-like, putative
— OG7
TcCLB.504153.310 ⚠
heat shock protein, putative
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TcCLB.511555.60
ubiquitin ligase, putative
— Both
TcCLB.506147.30 ⚠
synaptojanin (N-terminal domain), putative, i
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.511707.39 ⚠
Importin subunit beta-4, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.