TcCLB.506251.100

poly(A)-specific ribonuclease PARN, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102215 OG7: OG7_0005534 155 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 155 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511067.10 ⚠
tubulin folding cofactor D, putative
— Both
TcCLB.506183.9 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
TcCLB.507537.30 ⚠
cysteinyl-tRNA synthetase, putative
— Both
TcCLB.506531.60 ⚠
hypothetical protein, conserved
— Both
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.509803.40 ⚠
5-oxoprolinase, putative
— Both
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508271.10 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
TcCLB.511421.110 ⚠
developmentally regulated phosphoprotein, put
— Both
TcCLB.509597.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506635.70 ⚠
Zeta toxin, putative
— Both
TcCLB.509073.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— Both
TcCLB.503467.9 ⚠
NADH-dependent fumarate reductase, putative (
— Both
TcCLB.511575.40 ⚠
exonuclease, putative
— Both
TcCLB.506649.100 ⚠
tRNA nucleotidyltransferase, putative
— Both
TcCLB.503841.80 ⚠
NADH-dependent fumarate reductase, putative
— Both
TcCLB.439653.10 ⚠
NADH-dependent fumarate reductase, putative
— OG6
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcCLB.503589.10 ⚠
GDP-mannose pyrophosphorylase
— Both
TcCLB.503855.40 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
TcCLB.506625.60 ⚠
inositol 5-phosphatase 1, putative
— Both
TcCLB.503747.10 ⚠
glutamine aminotransferase, putative (fragmen
— Both
TcCLB.511585.40 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
TcCLB.511001.190 ⚠
vacuolar ATP synthase subunit d, putative
— Both
TcCLB.510741.220 ⚠
hypothetical protein, conserved
— Both
TcCLB.506563.220 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
TcCLB.511571.40 ⚠
hypothetical protein, conserved
— Both
TcCLB.511555.60 ⚠
ubiquitin ligase, putative
— Both
TcCLB.508535.10 ⚠
NADH-dependent fumarate reductase, putative
— Both
TcCLB.508207.230 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TcCLB.506773.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— OG7
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— OG7
TcCLB.509805.220 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
TcCLB.509103.20 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcCLB.506779.100 ⚠
RNA-binding protein, putative
— OG7
TcCLB.506775.30 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.506775.50 ⚠
Domain of unknown function(DUF2779), putative
— OG7
TcCLB.506743.210 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.504163.50 ⚠
fructose-bisphosphate aldolase, glycosomal, p
— OG7
TcCLB.508357.40 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.503865.40 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcCLB.508535.50 ⚠
tyrosine aminotransferase
— OG7
TcCLB.510101.150 ⚠
adaptin-related protein-like, putative
— OG7
TcCLB.506673.60 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.