TcCLB.506563.220

calpain-like cysteine peptidase, putative, cysteine peptidase, Clan CA, family C2, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_127587 OG7: OG7_0001161 118 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 118 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509777.100 ⚠
ubiquitin-activating enzyme, putative
— OG6
TcCLB.508463.29 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG6
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— OG6
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— OG6
TcCLB.508207.230 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG6
TcCLB.504089.50 ⚠
Flagellar radial spoke protein 4/6
— OG6
TcCLB.506405.120 ⚠
V-type ATPase, A subunit, putative
— OG6
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— OG6
TcCLB.509805.210 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506503.120 ⚠
hypothetical protein, conserved
— OG6
TcCLB.509769.30 ⚠
Inositol hexakisphosphate, putative
— OG6
TcCLB.503525.20 ⚠
Cyclin 12, L-type
— OG6
TcCLB.508515.30 ⚠
RNA-binding protein 38, putative
— OG6
TcCLB.507011.250 ⚠
Putative death-receptor fusion protein (DUF24
— OG6
TcCLB.511737.20 ⚠
hypothetical protein, conserved
— OG6
TcCLB.504171.50 ⚠
hypothetical protein, conserved
— OG6
TcCLB.509099.150 ⚠
cdc2-related kinase 9
— OG6
TcCLB.511211.110 ⚠
hypothetical protein, conserved
— OG6
TcCLB.507669.50 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506933.60 ⚠
mitochondrial RNA binding protein, putative
— OG6
TcCLB.503449.30 ⚠
clathrin coat assembly protein, putative
— OG6
TcCLB.418069.10 ⚠
heat shock protein 70 (hsp70), putative (frag
— OG6
TcCLB.506135.9 ⚠
heat shock 70 kDa protein, putative (fragment
— OG6
TcCLB.511211.160 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.511211.220 ⚠
heat shock protein 70, putative
— OG6
TcCLB.511211.170 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.509543.50 ⚠
DNAK protein, putative
— OG6
TcCLB.508813.15 ⚠
heat shock protein 70, putative (fragment)
— OG6
TcCLB.511585.40 ⚠
DNA-damage inducible protein DDI1-like protei
— OG6
TcCLB.503885.90 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG6
TcCLB.511421.110 ⚠
developmentally regulated phosphoprotein, put
— OG6
TcCLB.508387.160 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG6
TcCLB.503697.60 ⚠
nuclear cap binding complex subunit CBP110, p
— OG6
TcCLB.511545.140 ⚠
hypothetical protein, conserved
— OG6
TcCLB.507993.280 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— OG6
TcCLB.511001.190 ⚠
vacuolar ATP synthase subunit d, putative
— OG6
TcCLB.503689.40 ⚠
hypothetical protein, conserved
— OG6
TcCLB.508347.120 ⚠
hypothetical protein, conserved
— OG6
TcCLB.508277.100 ⚠
cAMP specific phosphodiesterase, putative
— OG6
TcCLB.508277.110 ⚠
cAMP specific phosphodiesterase, putative
— OG6
TcCLB.506859.70 ⚠
guide RNA associated protein, GAP2, putative
— OG6
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG6
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG6
TcCLB.506747.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG6
TcCLB.507925.69 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506363.70 ⚠
amidohydrolase, putative
— OG6
TcCLB.506363.90 ⚠
amidohydrolase, putative
— OG6
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG6
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG6
TcCLB.510089.50 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.