TcCLB.503613.60

acidocalcisomal pyrophosphatase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100346 OG7: OG7_0003350 283 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 283 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511585.130 ⚠
ubiquitin activating enzyme, putative
— OG7
TcCLB.507993.390 ⚠
pyruvate kinase 2, putative
— Both
TcCLB.509777.100 ⚠
ubiquitin-activating enzyme, putative
— Both
TcCLB.510957.9 ⚠
calpain-like cysteine peptidase, putative
— OG6
TcCLB.506563.190 ⚠
calpain-like cysteine peptidase, putative
— OG6
TcCLB.503589.10 ⚠
GDP-mannose pyrophosphorylase
— Both
TcCLB.503855.40 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
TcCLB.506563.220 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
TcCLB.509247.50 ⚠
methionyl-tRNA synthetase, putative
— Both
TcCLB.510777.29 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.511305.10 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.511351.41 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511353.4 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.507211.10 ⚠
choline/carnitine O-acyltransferase, putative
— OG7
TcCLB.511303.40 ⚠
carnitine O-acetyltransferase, putative
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.511627.120 ⚠
aldo/keto reductase, putative
— OG7
TcCLB.511529.100 ⚠
Methyltransferase TYW3, putative
— OG7
TcCLB.507993.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510841.10 ⚠
Kinesin-13 4b, putative (fragment)
— OG7
TcCLB.505123.28 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.508921.30 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.509589.30 ⚠
Kinesin-13 5, putative
— OG7
TcCLB.506895.40 ⚠
Kinesin-13 1, putative
— OG7
TcCLB.504153.140 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcCLB.508207.230 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TcCLB.509669.90 ⚠
XPC-binding domain/UBA/TS-N domain containing
— Both
TcCLB.509551.70 ⚠
Co-chaperone protein P23
— Both
TcCLB.509453.4 ⚠
hypothetical protein, conserved
— Both
TcCLB.504147.30 ⚠
Protein of unknown function (DUF2870), putati
— Both
TcCLB.507941.100 ⚠
hypothetical protein, conserved
— Both
TcCLB.508535.10 ⚠
NADH-dependent fumarate reductase, putative
— Both
TcCLB.511555.60 ⚠
ubiquitin ligase, putative
— Both
TcCLB.511571.40 ⚠
hypothetical protein, conserved
— Both
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— Both
TcCLB.508387.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.509153.120 ⚠
acyl-CoA dehydrogenase, putative
— Both
TcCLB.503841.80 ⚠
NADH-dependent fumarate reductase, putative
— Both
TcCLB.508089.30 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
TcCLB.510053.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— Both
TcCLB.509011.40 ⚠
calreticulin, putative
— Both
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
TcCLB.507809.60 ⚠
hypothetical protein, conserved
— Both
TcCLB.511575.40 ⚠
exonuclease, putative
— Both
TcCLB.439653.10 ⚠
NADH-dependent fumarate reductase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.