TcCLB.510053.70

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101202 OG7: OG7_0002064 202 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 202 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506945.80 ⚠
DNA ligase I, putative
— Both
TcCLB.504867.20 ⚠
ABC transporter, putative
— OG7
TcCLB.510601.30 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcCLB.506367.20 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcCLB.506743.220 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506745.4 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.509103.4 ⚠
protein kinase, putative
— OG7
TcCLB.506513.50 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcCLB.506467.50 ⚠
serine/threonine protein kinase, putative
— OG7
TcCLB.504421.10 ⚠
serine/threonine protein kinase, putative
— OG7
TcCLB.506467.40 ⚠
serine/threonine protein kinase, putative
— OG7
TcCLB.506505.40 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG7
TcCLB.506885.270 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.510141.20 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcCLB.506941.80 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.508995.30 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcCLB.506743.210 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.506775.30 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.505945.30 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.509103.20 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcCLB.505945.20 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.510609.30 ⚠
GTPase, putative
— OG7
TcCLB.510351.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506287.150 ⚠
GTP-binding protein, putative
— OG7
TcCLB.504153.300 ⚠
GTPase protein, putative
— OG7
TcCLB.503407.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.504147.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510257.80 ⚠
cytosolic nonspecific dipeptidase, putative
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511191.10 ⚠
tyrosyl-DNA Phosphodiesterase (Tdp1), putativ
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.506773.150 ⚠
hypothetical protein
— OG7
TcCLB.503489.10 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcCLB.510747.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506375.70 ⚠
Fungal tRNA ligase phosphodiesterase domain c
— OG7
TcCLB.508583.10 ⚠
Methyltransferase domain/Methyltransferase in
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.510749.4 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.509167.150 ⚠
homoserine kinase
— OG7
TcCLB.508375.30 ⚠
aspartate carbamoyltransferase, putative
— OG7
TcCLB.507091.50 ⚠
aspartate carbamoyltransferase, putative
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.510737.100 ⚠
Peroxin 19
— OG7
TcCLB.510879.40 ⚠
Carboxypeptidase-like protein
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.507993.369 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
TcCLB.511801.20 ⚠
D123, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.