TcCLB.508995.30

tubulin-tyrosine ligase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_137036 OG7: OG7_0001164 138 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 138 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507639.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508921.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509069.49 ⚠
DNA replication licensing factor MCM7, putati
— OG7
TcCLB.509199.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506649.80 ⚠
Double RNA binding domain protein 3
— OG7
TcCLB.503529.10 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.506265.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507757.70 ⚠
dihydrolipoamide dehydrogenase, putative, ace
— OG7
TcCLB.508239.30 ⚠
neurobeachin/beige-like protein, putative
— OG7
TcCLB.506773.150 ⚠
hypothetical protein
— OG7
TcCLB.506203.80 ⚠
formin-like protein
— OG7
TcCLB.509157.80 ⚠
DnaJ homolog, putative
— OG7
TcCLB.403789.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.507527.30 ⚠
DNA replication licensing factor MCM6, putati
— OG7
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.510285.20 ⚠
PQQ-like domain/WD domain, G-beta repeat/Utp2
— OG7
TcCLB.447255.4 ⚠
ubiquitin, putative
— OG7
TcCLB.506525.162 ⚠
Flagellum attachment zone protein 9 (fragment
— OG7
TcCLB.508647.140 ⚠
DNA replication licensing factor MCM5, putati
— OG7
TcCLB.511043.30 ⚠
DnaJ chaperone protein, putative, heat shock
— OG7
TcCLB.443683.9 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.507625.110 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.506529.260 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.503833.20 ⚠
chaperone protein DnaJ, putative
— OG7
TcCLB.506925.40 ⚠
RNA polymerase I second largest subunit, puta
— OG7
TcCLB.506633.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503637.20 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcCLB.506527.4 ⚠
Flagellum attachment zone protein 9 (fragment
— OG7
TcCLB.503407.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507077.30 ⚠
DnaJ domain containing protein, putative
— OG7
TcCLB.510101.150 ⚠
adaptin-related protein-like, putative
— OG7
TcCLB.510771.9 ⚠
Thioredoxin-like/Protein of unknown function
— OG7
TcCLB.414517.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.506673.60 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcCLB.506775.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511867.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511071.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510293.50 ⚠
DnaJ chaperone protein, putative
— OG7
TcCLB.506931.30 ⚠
DnaJ domain containing protein, putative
— OG7
TcCLB.504163.50 ⚠
fructose-bisphosphate aldolase, glycosomal, p
— OG7
TcCLB.504163.40 ⚠
fructose-bisphosphate aldolase, glycosomal, p
— OG7
TcCLB.506893.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509297.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506625.200 ⚠
exosome complex exonuclease, putative, riboso
— OG7
TcCLB.506773.130 ⚠
pumilio-repeat, RNA-binding protein, putative
— OG7
TcCLB.506779.100 ⚠
RNA-binding protein, putative
— OG7
TcCLB.506661.110 ⚠
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— OG7
TcCLB.508567.70 ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
TcCLB.506857.60 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.