TcCLB.508567.70

peptidyl-prolyl cis-trans isomerase
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100390 OG7: OG7_0003241 36 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 36 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511043.30 ⚠
DnaJ chaperone protein, putative, heat shock
— OG7
TcCLB.506775.30 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.506265.45 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.511871.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509809.20 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.511109.90 ⚠
DnaJ chaperone protein, putative
— OG7
TcCLB.509157.80 ⚠
DnaJ homolog, putative
— OG7
TcCLB.506743.210 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.508995.30 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcCLB.509103.20 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcCLB.506941.80 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.507625.110 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.506529.260 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.507077.30 ⚠
DnaJ domain containing protein, putative
— OG7
TcCLB.510141.20 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcCLB.506885.270 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.511217.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506931.30 ⚠
DnaJ domain containing protein, putative
— OG7
TcCLB.510293.50 ⚠
DnaJ chaperone protein, putative
— Both
TcCLB.507091.40 ⚠
dihydroorotate dehydrogenase, putative
— OG6
TcCLB.508375.50 ⚠
dihydroorotate dehydrogenase (fumarate), puta
— OG6
TcCLB.506649.80 ⚠
Double RNA binding domain protein 3
— Both
TcCLB.509499.10 ⚠
cyclophilin, putative, peptidyl-prolyl cis-tr
— OG6
TcCLB.510259.50 ⚠
21 kDa cyclophilin, putative, PPIase, putativ
— OG6
TcCLB.503833.20 ⚠
chaperone protein DnaJ, putative
— Both
TcCLB.506925.300 ⚠
cyclophilin a, putative
— OG6
TcCLB.511111.30 ⚠
Domain of unknown function (DUF4520), putativ
— Both
TcCLB.509297.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.506553.20 ⚠
bromodomain factor 2 protein
— OG6
TcCLB.503841.70 ⚠
aspartate aminotransferase, putative
— OG6
TcCLB.504077.40 ⚠
translation elongation factor EF-2, putative
— OG6
TcCLB.506795.50 ⚠
poly(A) polymerase, putative, polynucleotide
— OG6
TcCLB.506893.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.509591.20 ⚠
kinetoplastid-specific phospho-protein phosph
— OG6
TcCLB.508585.29 ⚠
kinetoplastid-specific phospho-protein phosph
— OG6
TcCLB.510879.10 ⚠
serine/threonine-protein phosphatase 2A, cata
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.