TcCLB.506743.210

tubulin tyrosine ligase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_104876 OG7: OG7_0001164 137 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 137 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509769.134 ⚠
Beta-lactamase superfamily domain containing
— OG7
TcCLB.511127.140 ⚠
DNA replication licensing factor MCM4, putati
— OG7
TcCLB.511313.30 ⚠
formin, putative
— OG7
TcCLB.506265.45 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.506107.20 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcCLB.504203.29 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcCLB.504427.250 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.511113.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.510257.80 ⚠
cytosolic nonspecific dipeptidase, putative
— OG7
TcCLB.503425.29 ⚠
DNA replication licensing factor MCM8, putati
— OG7
TcCLB.511747.30 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
TcCLB.511871.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509809.20 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.510053.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510293.40 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcCLB.511803.10 ⚠
cullin 2, putative
— OG7
TcCLB.511217.100 ⚠
cullin 3, putative
— OG7
TcCLB.511109.100 ⚠
DNA replication licensing factor MCM3, putati
— OG7
TcCLB.506927.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511109.90 ⚠
DnaJ chaperone protein, putative
— OG7
TcCLB.511191.10 ⚠
tyrosyl-DNA Phosphodiesterase (Tdp1), putativ
— OG7
TcCLB.510409.39 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcCLB.509069.49 ⚠
DNA replication licensing factor MCM7, putati
— OG7
TcCLB.506649.80 ⚠
Double RNA binding domain protein 3
— OG7
TcCLB.506265.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507757.70 ⚠
dihydrolipoamide dehydrogenase, putative, ace
— OG7
TcCLB.508239.30 ⚠
neurobeachin/beige-like protein, putative
— OG7
TcCLB.506773.150 ⚠
hypothetical protein
— OG7
TcCLB.509157.80 ⚠
DnaJ homolog, putative
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.507527.30 ⚠
DNA replication licensing factor MCM6, putati
— OG7
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.508647.140 ⚠
DNA replication licensing factor MCM5, putati
— OG7
TcCLB.504163.40 ⚠
fructose-bisphosphate aldolase, glycosomal, p
— OG7
TcCLB.511393.30 ⚠
formin homology 2 (FH2) domain protein, putat
— OG7
TcCLB.511075.40 ⚠
cullin, putative
— OG7
TcCLB.511115.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511217.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511867.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510293.50 ⚠
DnaJ chaperone protein, putative
— OG7
TcCLB.506931.30 ⚠
DnaJ domain containing protein, putative
— OG7
TcCLB.504163.50 ⚠
fructose-bisphosphate aldolase, glycosomal, p
— OG7
TcCLB.505983.30 ⚠
general transcription factor IIB
— OG7
TcCLB.506779.100 ⚠
RNA-binding protein, putative
— OG7
TcCLB.508567.70 ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
TcCLB.506857.60 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.511051.59 ⚠
Thiamin pyrophosphokinase, vitamin B1 binding
— OG7
TcCLB.506893.50 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.