TcCLB.506927.20

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_388959 OG7: OG7_0063820 75 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 75 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510141.20 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcCLB.510257.80 ⚠
cytosolic nonspecific dipeptidase, putative
— OG7
TcCLB.511747.30
C2H2 type zinc-finger (2 copies), putative
— OG7
TcCLB.504203.29 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcCLB.506107.20 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcCLB.509167.100
valyl-tRNA synthetase, putative
— OG7
TcCLB.511051.59
Thiamin pyrophosphokinase, vitamin B1 binding
— OG7
TcCLB.510879.50 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcCLB.507035.110 ⚠
cAMP response protein 1, putative
— OG7
TcCLB.506885.270 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.510053.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506941.80 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.508995.30 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcCLB.506743.210 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.506775.30 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.505945.30 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.509103.20 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcCLB.505945.20 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.503407.10
hypothetical protein, conserved
— OG7
TcCLB.509967.80 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.503865.40 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcCLB.506735.10 ⚠
metallo-peptidase, Clan ME, Family M16, putat
— OG7
TcCLB.505983.30
general transcription factor IIB
— OG7
TcCLB.504147.80 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcCLB.419469.30
hypothetical protein, conserved
— OG7
TcCLB.511801.20
D123, putative
— OG7
TcCLB.506945.80
DNA ligase I, putative
— OG7
TcCLB.506773.150 ⚠
hypothetical protein
— OG7
TcCLB.506265.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511191.10
tyrosyl-DNA Phosphodiesterase (Tdp1), putativ
— OG7
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— Both
TcCLB.507547.30 ⚠
Mitochondrial-processing peptidase subunit al
— Both
TcCLB.506227.150 ⚠
protein kinase A regulatory subunit
— Both
TcCLB.506411.10 ⚠
metallo-peptidase, clan MA(E), family M3, put
— Both
TcCLB.511589.200
S-adenosylhomocysteine hydrolase, putative
— Both
TcCLB.503991.20
Xaa-Pro aminopeptidase, putative
— Both
TcCLB.506483.69 ⚠
mitogen activated protein kinase 4, putative,
— OG6
TcCLB.508569.80
phosphoacetylglucosamine mutase, putative
— Both
TcCLB.504047.5
urocanate hydratase, putative (fragment)
— Both
TcCLB.506811.190
UDP-galactose 4-epimerase
— Both
TcCLB.511743.30
hypothetical protein, conserved
— Both
TcCLB.510123.20 ⚠
mitogen-activated protein kinase 11, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.