TcCLB.507547.30

Mitochondrial-processing peptidase subunit alpha
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102381 OG7: OG7_0001887 85 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 85 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG7
TcCLB.506753.110 ⚠
cytochrome b5-like protein, putative
— OG7
TcCLB.503557.20 ⚠
ankyrin repeat protein, putative
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— OG7
TcCLB.507047.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509805.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506773.44 ⚠
cytochrome b5, putative
— OG7
TcCLB.510879.50 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcCLB.507035.110 ⚠
cAMP response protein 1, putative
— OG7
TcCLB.504147.80 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506287.30 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.511181.50 ⚠
mitochondrial processing peptidase, beta subu
— OG7
TcCLB.511801.34 ⚠
NADH dehydrogenase subunit NB6M, putative
— OG7
TcCLB.509803.40 ⚠
5-oxoprolinase, putative
— Both
TcCLB.508927.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.510741.220 ⚠
hypothetical protein, conserved
— Both
TcCLB.511589.200 ⚠
S-adenosylhomocysteine hydrolase, putative
— Both
TcCLB.506755.50 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcCLB.506493.50 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
TcCLB.511001.60 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.511801.14 ⚠
protein lipid droplet kinase (LDK)
— OG7
TcCLB.504125.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.464807.10 ⚠
serine/threonine protein kinase, putative, CA
— OG7
TcCLB.510861.140 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.510257.130 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcCLB.510525.10 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcCLB.507509.80 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcCLB.506755.90 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcCLB.510101.490 ⚠
anion-transporting ATPase-like, putative
— Both
TcCLB.503653.60 ⚠
cytochrome b-domain protein, putative
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.510611.40 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— OG7
TcCLB.509805.220 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
TcCLB.503865.40 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcCLB.508535.50 ⚠
tyrosine aminotransferase
— OG7
TcCLB.504431.109 ⚠
cytochrome b5, putative
— OG7
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.509149.9 ⚠
cystathionine beta-synthase, serine sulfhydry
— Both
TcCLB.508537.5 ⚠
tyrosine aminotransferase, putative (fragment
— Both
TcCLB.510565.11 ⚠
tyrosine aminotransferase, putative (fragment
— Both
TcCLB.506207.40 ⚠
WD domain, G-beta repeat, putative
— Both
TcCLB.506227.150 ⚠
protein kinase A regulatory subunit
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.