TcCLB.503557.20

ankyrin repeat protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100012 OG7: OG7_0000441 136 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 136 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510053.60 ⚠
cytidine deaminase-like protein, putative
— OG7
TcCLB.508387.90 ⚠
paraflagellar rod protein, putative
— OG7
TcCLB.506885.416 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511111.20 ⚠
hypothetical protein
— OG7
TcCLB.506893.80 ⚠
monothiol glutaredoxin, putative
— OG7
TcCLB.503425.20 ⚠
monothiol glutaredoxin, putative
— OG7
TcCLB.511179.100 ⚠
monothiol glutaredoxin, putative
— OG7
TcCLB.506563.160 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
TcCLB.450155.9 ⚠
Nucleoporin NUP76
— OG7
TcCLB.506941.9 ⚠
endosomal trafficking protein RME-8, putative
— OG7
TcCLB.503885.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507389.10 ⚠
Flagellum attachment zone protein 14
— OG7
TcCLB.508647.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510507.50 ⚠
RNA-binding protein, putative
— OG7
TcCLB.503909.120 ⚠
cyclosome subunit, putative
— OG7
TcCLB.511527.9 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
TcCLB.503885.10 ⚠
Nucleoporin NUP76
— OG7
TcCLB.398751.10 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
TcCLB.506925.180 ⚠
protein kinase, putative
— OG7
TcCLB.506399.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506265.150 ⚠
Uncharacterised ACR, YggU family COG1872, put
— OG7
TcCLB.506465.40 ⚠
protein kinase-like protein, putative
— OG7
TcCLB.506925.30 ⚠
Regulatory-associated protein of TOR1
— OG7
TcCLB.508837.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510325.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510105.120 ⚠
protein kinase, putative
— OG7
TcCLB.511747.7 ⚠
cyclosome subunit, putative (fragment)
— OG7
TcCLB.507035.110 ⚠
cAMP response protein 1, putative
— OG7
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.507993.140 ⚠
RNA-binding protein 29, putative
— OG7
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.503865.40 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcCLB.510741.220 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509803.40 ⚠
5-oxoprolinase, putative
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.507603.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508927.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503515.14 ⚠
ubiquitin-conjugating enzyme E2, putative
— OG7
TcCLB.504033.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506207.40 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.506227.150 ⚠
protein kinase A regulatory subunit
— OG7
TcCLB.510879.50 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcCLB.510091.100 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.