TcCLB.510091.100

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_158193 OG7: OG7_0052300 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506147.100
Spindle assembly abnormal protein 6 homolog
— Both
TcCLB.510741.220
hypothetical protein, conserved
— Both
TcCLB.507711.280
hypothetical protein, conserved
— Both
TcCLB.507993.140
RNA-binding protein 29, putative
— Both
TcCLB.504149.140
hypothetical protein, conserved
— Both
TcCLB.508207.200
small GTP-binding protein, putative
— Both
TcCLB.511577.90
pseudouridylate synthase-like protein, putati
— Both
TcCLB.506181.40
Uncharacterized ACR, COG1678, putative
— Both
TcCLB.511675.3 ⚠
Trypomastigote, Alanine, Serine and Valine ri
— OG6
TcCLB.511041.4 ⚠
Sucrase/ferredoxin-like, putative
— Both
TcCLB.509147.40 ⚠
Trypomastigote, Alanine, Serine and Valine ri
— OG6
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.511613.120 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.511603.200 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.510531.30
Galactose oxidase, central domain containing
— OG6
TcCLB.506163.35
hypothetical protein, conserved
— Both
TcCLB.508729.18 ⚠
Sucrase/ferredoxin-like, putative
— Both
TcCLB.511139.20 ⚠
40S ribosomal protein S11, putative
— Both
TcCLB.507547.30 ⚠
Mitochondrial-processing peptidase subunit al
— Both
TcCLB.507837.50 ⚠
40S ribosomal protein S11, putative
— Both
TcCLB.510517.30
hypothetical protein, conserved
— Both
TcCLB.511739.20
Mitochondrial large ribosomal subunit mL72, p
— Both
TcCLB.509231.39 ⚠
zinc finger protein 3
— OG7
TcCLB.510609.30 ⚠
GTPase, putative
— OG7
TcCLB.510351.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506287.150 ⚠
GTP-binding protein, putative
— OG7
TcCLB.504153.300 ⚠
GTPase protein, putative
— OG7
TcCLB.511545.100 ⚠
RNA methyltransferase, putative
— OG7
TcCLB.503865.40 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcCLB.509151.80 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcCLB.510611.40 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcCLB.503557.20 ⚠
ankyrin repeat protein, putative
— OG7
TcCLB.509805.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508323.110
Mitochondrial large ribosomal subunit mL71, p
— Both
TcCLB.506739.99 ⚠
zinc finger (CCCH type) protein, putative
— OG7
TcCLB.504929.5 ⚠
zinc finger CCCH domain containing protein 11
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.506735.10 ⚠
metallo-peptidase, Clan ME, Family M16, putat
— OG7
TcCLB.507629.39
hypothetical protein, conserved (fragment)
— OG7
TcCLB.509805.220
cholinephosphate cytidylyltransferase A, puta
— OG7
TcCLB.507093.300
hypothetical protein SCD6.10
— OG7
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— OG7
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.508469.20
hypothetical protein, conserved
— Both
TcCLB.484311.10 ⚠
calpain-like cysteine peptidase, putative (fr
— Both
TcCLB.504107.10 ⚠
calpain-like cysteine peptidase, putative (fr
— Both
TcCLB.509777.80
hypothetical protein, conserved
— Both
TcCLB.407477.60
hypothetical protein, conserved
— Both
TcCLB.508211.70
Protein of unknown function (DUF525), putativ
— Both
TcCLB.507669.110
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.