TcCLB.510879.50

regulatory subunit of protein kinase a-like protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_119433 OG7: OG7_0001574 162 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 162 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506885.430 ⚠
lipoic acid containing carrier protein, putat
— OG7
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— OG7
TcCLB.507603.200 ⚠
proteasome regulatory ATPase subunit 3, putat
— OG7
TcCLB.506885.416 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcCLB.506563.160 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
TcCLB.509247.30 ⚠
CCR4-NOT transcription complex subunit 1
— OG7
TcCLB.507213.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504057.104 ⚠
phosphatidylinositol phosphate kinase alpha
— OG7
TcCLB.510161.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511143.12 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.450155.9 ⚠
Nucleoporin NUP76
— OG7
TcCLB.510159.19 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.508215.10 ⚠
zinc finger CCCH domain containing protein 17
— OG7
TcCLB.510309.20 ⚠
MFS transporter, putative
— OG7
TcCLB.507739.20 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.506941.9 ⚠
endosomal trafficking protein RME-8, putative
— OG7
TcCLB.504009.40 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcCLB.506289.50 ⚠
Nucleolar protein 105, putative
— OG7
TcCLB.510311.70 ⚠
26S protease regulatory subunit, putative, se
— OG7
TcCLB.506859.20 ⚠
proteasome regulatory ATPase subunit 5, putat
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503885.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506211.70 ⚠
RNA-binding protein, putative
— OG7
TcCLB.507389.10 ⚠
Flagellum attachment zone protein 14
— OG7
TcCLB.508647.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507735.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504147.200 ⚠
19S proteasome regulatory subunit, Regulatory
— OG7
TcCLB.503909.120 ⚠
cyclosome subunit, putative
— OG7
TcCLB.511047.50 ⚠
proteasome regulatory ATPase subunit 2, putat
— OG7
TcCLB.504029.101 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511527.9 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
TcCLB.503885.10 ⚠
Nucleoporin NUP76
— OG7
TcCLB.510289.30 ⚠
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
TcCLB.506211.60 ⚠
RNA-binding protein, putative
— OG7
TcCLB.506857.90 ⚠
proteasome regulatory ATPase subunit 1, putat
— OG7
TcCLB.398751.10 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.509805.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508953.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507529.10 ⚠
Cell growth-regulating nucleolar protein, put
— OG7
TcCLB.505807.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509599.20 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
TcCLB.510515.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504835.29 ⚠
Flagellum attachment zone protein 14
— OG7
TcCLB.507509.89 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcCLB.511747.7 ⚠
cyclosome subunit, putative (fragment)
— OG7
TcCLB.510105.120 ⚠
protein kinase, putative
— OG7
TcCLB.509967.170 ⚠
dynein arm light chain, putative
— OG7
TcCLB.511365.10 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.