TcCLB.507213.10

hypothetical protein, conserved

Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_139691 OG7: OG7_0000949 97 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 97 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcCLB.510311.70 ⚠ 26S protease regulatory subunit, putative, se	—	OG7 LdBPK_030520.1 ↔ LdBPK_364570.1 OG7 LdBPK_130990.1 ↔ LdBPK_364570.1 OG7 LdBPK_220440.1 ↔ LdBPK_364570.1 OG7 LdBPK_220490.1 ↔ LdBPK_364570.1 +41 more	OG7
TcCLB.507603.200 ⚠ proteasome regulatory ATPase subunit 3, putat	—	OG7 LdBPK_030520.1 ↔ LdBPK_364570.1 OG7 LdBPK_130990.1 ↔ LdBPK_364570.1 OG7 LdBPK_220440.1 ↔ LdBPK_364570.1 OG7 LdBPK_220490.1 ↔ LdBPK_364570.1 +41 more	OG7
TcCLB.506223.80 ⚠ Metalloprotease M41 FtsH, putative	—	OG7 LdBPK_030520.1 ↔ LdBPK_364570.1 OG7 LdBPK_130990.1 ↔ LdBPK_364570.1 OG7 LdBPK_220440.1 ↔ LdBPK_364570.1 OG7 LdBPK_220490.1 ↔ LdBPK_364570.1 +41 more	OG7
TcCLB.509489.29 ⚠ proteasome regulatory non-ATP-ase subunit, pu	—	OG7 LdBPK_321260.1 ↔ LdBPK_364570.1 OG7 Tb927.11.14430 ↔ Tb927.11.3740 OG7 Tb927.11.14430 ↔ Tb927.7.2550 OG7 Tb927.11.14430 ↔ Tb927.7.2500 +14 more	OG7
TcCLB.507739.20 ⚠ mitochondrial ATP-dependent zinc metallopepti	—	OG7 LdBPK_030520.1 ↔ LdBPK_364570.1 OG7 LdBPK_130990.1 ↔ LdBPK_364570.1 OG7 LdBPK_220440.1 ↔ LdBPK_364570.1 OG7 LdBPK_220490.1 ↔ LdBPK_364570.1 +41 more	OG7
TcCLB.503513.40 ⚠ proteasome regulatory non-ATPase subunit 6, p	—	OG7 Tb927.2.2440 ↔ Tb927.7.2550 OG7 Tb927.2.2440 ↔ Tb927.7.2500 OG7 Tb927.2.2440 ↔ Tb927.6.1090 OG7 LdBPK_020340.1 ↔ LdBPK_364570.1 +14 more	OG7
TcCLB.509073.119 ⚠ proteasome regulatory non-ATP-ase subunit 7,	—	OG7 TCSYLVIO_005383 ↔ TCSYLVIO_006982 OG7 LdBPK_030520.1 ↔ LdBPK_322960.1 OG7 LdBPK_130990.1 ↔ LdBPK_322960.1 OG7 LdBPK_220440.1 ↔ LdBPK_322960.1 +14 more	OG7
TcCLB.510105.210 ⚠ mitochondrial ATP-dependent zinc metallopepti	—	OG7 LdBPK_030520.1 ↔ LdBPK_364570.1 OG7 LdBPK_130990.1 ↔ LdBPK_364570.1 OG7 LdBPK_220440.1 ↔ LdBPK_364570.1 OG7 LdBPK_220490.1 ↔ LdBPK_364570.1 +41 more	OG7
TcCLB.509649.30 ⚠ 19S proteasome non-atpase subunit 8	—	OG7 LdBPK_320400.1 ↔ LdBPK_364570.1 OG7 LdBPK_030520.1 ↔ LdBPK_320400.1 OG7 LdBPK_130990.1 ↔ LdBPK_320400.1 OG7 LdBPK_220440.1 ↔ LdBPK_320400.1 +9 more	OG7
TcCLB.511365.70 ⚠ proteasome regulatory non-ATP-ase subunit 9,	—	OG7 TCSYLVIO_005996 ↔ TCSYLVIO_006982 OG7 LdBPK_130990.1 ↔ LdBPK_191100.1 OG7 LdBPK_030520.1 ↔ LdBPK_191100.1 OG7 LdBPK_120190.1 ↔ LdBPK_191100.1 +14 more	OG7
TcCLB.506859.20 ⚠ proteasome regulatory ATPase subunit 5, putat	—	OG7 LdBPK_030520.1 ↔ LdBPK_364570.1 OG7 LdBPK_130990.1 ↔ LdBPK_364570.1 OG7 LdBPK_220440.1 ↔ LdBPK_364570.1 OG7 LdBPK_220490.1 ↔ LdBPK_364570.1 +41 more	OG7
TcCLB.504147.200 ⚠ 19S proteasome regulatory subunit, Regulatory	—	OG7 LdBPK_030520.1 ↔ LdBPK_364570.1 OG7 LdBPK_130990.1 ↔ LdBPK_364570.1 OG7 LdBPK_220440.1 ↔ LdBPK_364570.1 OG7 LdBPK_220490.1 ↔ LdBPK_364570.1 +41 more	OG7
TcCLB.510855.40 ⚠ proteasome regulatory non-ATPase subunit, put	—	OG7 LdBPK_071300.1 ↔ LdBPK_364570.1 OG7 LdBPK_071300.1 ↔ LdBPK_220490.1 OG7 LdBPK_071300.1 ↔ LdBPK_220440.1 OG7 LdBPK_071300.1 ↔ LdBPK_130990.1 +14 more	OG7
TcCLB.503697.9 ⚠ proteasome regulatory non-ATPase subunit 11,	—	OG7 TCSYLVIO_004531 ↔ TCSYLVIO_006982 OG7 TCSYLVIO_004531 ↔ TCSYLVIO_004751 OG7 LdBPK_340670.1 ↔ LdBPK_364570.1 OG7 Tb927.10.3030 ↔ Tb927.11.3740 +15 more	OG7
TcCLB.511047.50 ⚠ proteasome regulatory ATPase subunit 2, putat	—	OG7 LdBPK_030520.1 ↔ LdBPK_364570.1 OG7 LdBPK_130990.1 ↔ LdBPK_364570.1 OG7 LdBPK_220440.1 ↔ LdBPK_364570.1 OG7 LdBPK_220490.1 ↔ LdBPK_364570.1 +41 more	OG7
TcCLB.506857.90 ⚠ proteasome regulatory ATPase subunit 1, putat	—	OG7 LdBPK_030520.1 ↔ LdBPK_364570.1 OG7 LdBPK_130990.1 ↔ LdBPK_364570.1 OG7 LdBPK_220440.1 ↔ LdBPK_364570.1 OG7 LdBPK_220490.1 ↔ LdBPK_364570.1 +41 more	OG7
TcCLB.511365.10 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_005994 ↔ TCSYLVIO_006982 OG7 LdBPK_220440.1 ↔ LdBPK_330300.1 OG7 TCSYLVIO_004491 ↔ TCSYLVIO_005994 OG7 TCSYLVIO_003002 ↔ TCSYLVIO_005994 +3 more	OG7
TcCLB.508389.20 ⚠ hypothetical protein	—	OG7 TCSYLVIO_001990 ↔ TCSYLVIO_006189	OG7
TcCLB.506885.320 ⚠ TPR repeat/Tetratricopeptide repeat, putative	—	OG7 TCSYLVIO_003731 ↔ TCSYLVIO_006189	OG7
TcCLB.509127.110 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003731 ↔ TCSYLVIO_006189	OG7
TcCLB.509381.10 ⚠ mitochondrial import receptor subunit, putati	—	OG7 TCSYLVIO_003731 ↔ TCSYLVIO_006189	OG7
TcCLB.509757.30 ⚠ stress-inducible protein STI1-like, putative	—	OG7 TCSYLVIO_003731 ↔ TCSYLVIO_006189	OG7
TcCLB.511627.100 ⚠ TPR-repeat protein, putative	—	OG7 TCSYLVIO_003731 ↔ TCSYLVIO_006189	OG7
TcCLB.509537.80 ⚠ TPR repeat, putative	—	OG7 TCSYLVIO_003731 ↔ TCSYLVIO_006189	OG7
TcCLB.507669.160 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003731 ↔ TCSYLVIO_006189	OG7
TcCLB.509595.40 ⚠ hypothetical protein, conserved	—	OG7 Tb927.11.8310 ↔ Tb927.7.2550 OG7 Tb927.11.8310 ↔ Tb927.7.2500 OG7 Tb927.11.8310 ↔ Tb927.6.1090 OG7 Tb927.10.9740 ↔ Tb927.11.8310 +2 more	OG7
TcCLB.509625.10 ⚠ ATP-dependent RNA helicase, putative (fragmen	—	OG7 TCSYLVIO_004491 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_003002 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_004751 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_001254 ↔ TCSYLVIO_008995 +2 more	OG7
TcCLB.510859.24 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006189 ↔ TCSYLVIO_009706	OG7
TcCLB.511315.9 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_004491 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_003002 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_004751 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_001254 ↔ TCSYLVIO_008995 +2 more	OG7
TcCLB.506963.80 ⚠ Nucleoporin NUP119	—	OG7 TCSYLVIO_006189 ↔ TCSYLVIO_009241	OG7
TcCLB.506179.59 ⚠ ATP-dependent RNA helicase, putative (fragmen	—	OG7 TCSYLVIO_004491 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_003002 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_004751 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_001254 ↔ TCSYLVIO_008995 +2 more	OG7
TcCLB.509769.70 ⚠ DNA polymerase theta (helicase domain only),	—	OG7 TCSYLVIO_004491 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_003002 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_004751 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_001254 ↔ TCSYLVIO_008995 +2 more	OG7
TcCLB.504051.20 ⚠ ATP-dependent DNA DEAD/DEAH box helicase, put	—	OG7 TCSYLVIO_004491 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_003002 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_004751 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_001254 ↔ TCSYLVIO_008995 +2 more	OG7
TcCLB.398751.10 ⚠ SPRY domain/HECT-domain (ubiquitin-transferas	—	OG7 TCSYLVIO_004491 ↔ TCSYLVIO_005364 OG7 TCSYLVIO_003002 ↔ TCSYLVIO_005364 OG7 TCSYLVIO_004751 ↔ TCSYLVIO_005364 OG7 TCSYLVIO_001254 ↔ TCSYLVIO_005364 +2 more	OG7
TcCLB.504449.30 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004491 ↔ TCSYLVIO_007057 OG7 TCSYLVIO_003002 ↔ TCSYLVIO_007057 OG7 TCSYLVIO_004751 ↔ TCSYLVIO_007057 OG7 TCSYLVIO_001254 ↔ TCSYLVIO_007057 +2 more	OG7
TcCLB.511527.9 ⚠ SPRY domain/HECT-domain (ubiquitin-transferas	—	OG7 TCSYLVIO_004491 ↔ TCSYLVIO_005364 OG7 TCSYLVIO_003002 ↔ TCSYLVIO_005364 OG7 TCSYLVIO_004751 ↔ TCSYLVIO_005364 OG7 TCSYLVIO_001254 ↔ TCSYLVIO_005364 +2 more	OG7
TcCLB.507813.10 ⚠ structural maintenance of chromosome 3 protei	—	OG7 LdBPK_211580.1 ↔ LdBPK_220440.1 OG7 LdBPK_050400.1 ↔ LdBPK_220440.1	OG7
TcCLB.509247.30 ⚠ CCR4-NOT transcription complex subunit 1	—	OG7 LdBPK_210880.1 ↔ LdBPK_220440.1	OG7
TcCLB.504033.180 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_040540.1 ↔ LdBPK_220440.1	OG7
TcCLB.506677.10 ⚠ ubiquitin-like protein, putative	—	OG7 TCSYLVIO_005459 ↔ TCSYLVIO_006189	OG7
TcCLB.503893.60 ⚠ UBA/TS-N domain containing protein, putative	—	OG7 TCSYLVIO_005459 ↔ TCSYLVIO_006189	OG7
TcCLB.510101.340 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_110830.1 ↔ LdBPK_220440.1	OG7
TcCLB.506227.150 ⚠ protein kinase A regulatory subunit	—	OG7 LdBPK_151180.1 ↔ LdBPK_220440.1	OG7
TcCLB.510879.50 ⚠ regulatory subunit of protein kinase a-like p	—	OG7 LdBPK_151180.1 ↔ LdBPK_220440.1	OG7
TcCLB.507035.110 ⚠ cAMP response protein 1, putative	—	OG7 LdBPK_151180.1 ↔ LdBPK_220440.1	OG7
TcCLB.503531.49 ⚠ structural maintenance of chromosome 3, putat	—	OG7 LdBPK_211580.1 ↔ LdBPK_220440.1 OG7 LdBPK_050400.1 ↔ LdBPK_220440.1	OG7
TcCLB.507011.60 ⚠ structural maintenance of chromosome (SMC) fa	—	OG7 LdBPK_211580.1 ↔ LdBPK_220440.1 OG7 LdBPK_050400.1 ↔ LdBPK_220440.1	OG7
TcCLB.511737.10 ⚠ small glutamine-rich tetratricopeptide repeat	—	OG7 TCSYLVIO_003731 ↔ TCSYLVIO_006189	OG7
TcCLB.508779.90 ⚠ structural maintenance of chromosome protein	—	OG7 LdBPK_211580.1 ↔ LdBPK_220440.1 OG7 LdBPK_050400.1 ↔ LdBPK_220440.1	OG7
TcCLB.507641.80 ⚠ 5'-3' exoribonuclease D, putative	—	OG7 LdBPK_060260.1 ↔ LdBPK_220440.1	OG7

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