TcCLB.509247.30

CCR4-NOT transcription complex subunit 1
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101511 OG7: OG7_0005420 84 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 84 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510073.70
CCR4-NOT transcription complex subunit 2, put
— +2 more Both
TcCLB.507873.20
cell differentiation protein, putative
— Both
TcCLB.510535.60
ccr4-not transcription complex subunit
— Both
TcCLB.504043.10
General negative regulator of transcription s
— Both
TcCLB.510165.10 ⚠
heat shock protein DNAJ, putative
— OG7
TcCLB.509835.20 ⚠
translation initiation factor eIF2B delta sub
— OG7
TcCLB.508179.10 ⚠
DnaJ chaperone protein, putative
— OG7
TcCLB.510743.100 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.510241.70 ⚠
heat shock protein, putative
— OG7
TcCLB.509233.80 ⚠
heat shock protein DNAJ, putative
— OG7
TcCLB.510101.340
hypothetical protein, conserved
— OG7
TcCLB.506227.150 ⚠
protein kinase A regulatory subunit
— OG7
TcCLB.510879.50 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcCLB.507035.110 ⚠
cAMP response protein 1, putative
— OG7
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— OG7
TcCLB.507011.60 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcCLB.511305.10 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.508647.210 ⚠
dynein arm light chain, putative
— OG7
TcCLB.504147.200 ⚠
19S proteasome regulatory subunit, Regulatory
— OG7
TcCLB.511627.110 ⚠
heat shock protein DNAJ, putative
— Both
TcCLB.508489.40
hypothetical protein, conserved
— OG7
TcCLB.509967.170 ⚠
dynein arm light chain, putative
— OG7
TcCLB.508837.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506223.80 ⚠
Metalloprotease M41 FtsH, putative
— OG7
TcCLB.510105.210 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.507099.40
Concanavalin A-like lectin/glucanases superfa
— OG7
TcCLB.504029.101
hypothetical protein, conserved
— OG7
TcCLB.511047.50 ⚠
proteasome regulatory ATPase subunit 2, putat
— OG7
TcCLB.511531.9 ⚠
chaperone DNAJ protein, putative
— OG7
TcCLB.503885.20
hypothetical protein, conserved
— OG7
TcCLB.506859.20 ⚠
proteasome regulatory ATPase subunit 5, putat
— OG7
TcCLB.510311.70 ⚠
26S protease regulatory subunit, putative, se
— OG7
TcCLB.504009.40 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcCLB.507739.20 ⚠
mitochondrial ATP-dependent zinc metallopepti
— OG7
TcCLB.511143.12 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcCLB.507213.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507603.200 ⚠
proteasome regulatory ATPase subunit 3, putat
— OG7
TcCLB.507257.180 ⚠
hypothetical protein
— OG7
TcCLB.510105.50 ⚠
fibrillarin, putative
— Both
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— Both
TcCLB.508989.70
hypothetical protein, conserved
— Both
TcCLB.504033.180
hypothetical protein, conserved
— Both
TcCLB.511605.30 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.506769.120 ⚠
Mucin-associated surface protein (MASP), subg
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.