TcCLB.509965.350

ubiquitin-protein ligase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100865 OG7: OG7_0000785 298 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 298 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504009.40 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcCLB.509967.170 ⚠
dynein arm light chain, putative
— OG7
TcCLB.506215.19 ⚠
intraflagellar transport protein 140, putativ
— OG7
TcCLB.510101.250 ⚠
hypothetical protein, conserved
— Both
TcCLB.508647.210 ⚠
dynein arm light chain, putative
— OG7
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.509769.70 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcCLB.504051.20 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcCLB.511313.40 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.503595.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509497.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510091.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507805.9 ⚠
histone deacetylase 4, putative
— OG7
TcCLB.507803.49 ⚠
histone deacetylase, putative
— OG7
TcCLB.503653.50 ⚠
histone deacetylase, putative
— OG7
TcCLB.507809.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506181.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503897.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504159.80 ⚠
histone deacetylase, putative
— OG7
TcCLB.510101.180 ⚠
40S ribosomal protein S5, putative
— OG7
TcCLB.510101.170 ⚠
40S ribosomal protein S5, putative
— OG7
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— OG7
TcCLB.511585.130 ⚠
ubiquitin activating enzyme, putative
— OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.508387.90 ⚠
paraflagellar rod protein, putative
— OG7
TcCLB.511531.40 ⚠
chaperonin alpha subunit, putative
— +4 more OG7
TcCLB.508357.90 ⚠
T-complex protein 1, beta subunit, putative
— +4 more OG7
TcCLB.505941.49 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506743.150 ⚠
proteasome 26S non-ATPase subunit 9, putative
— OG7
TcCLB.505943.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509583.10 ⚠
chaperonin TCP20, putative
— +4 more OG7
TcCLB.510515.139 ⚠
T-complex protein 1, gamma subunit, putative
— +4 more OG7
TcCLB.504181.50 ⚠
T-complex protein 1, delta subunit, putative
— +4 more OG7
TcCLB.510351.80 ⚠
Pre-mRNA polyadenylation factor FIP1
— OG7
TcCLB.510517.10 ⚠
chaperonin/T-complex protein 1 gamma subunit,
— +4 more OG7
TcCLB.509155.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507929.20 ⚠
co-chaperone GrpE, putative
— OG7
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.506525.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511115.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511111.10 ⚠
translation initiation factor IF-2, putative
— OG7
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.511353.40 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcCLB.506625.60 ⚠
inositol 5-phosphatase 1, putative
— OG7
TcCLB.507603.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510761.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511305.20 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcCLB.506659.10 ⚠
tc40 antigen-like, putative, immunodominant a
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.