TcCLB.510091.70

U6 snRNA-associated Sm-like protein LSm8, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102771 OG7: OG7_0001217 108 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 108 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.508973.50 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— +3 more Both
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.510741.180 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.503479.49 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— +2 more OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— +2 more OG7
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.511801.60 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
TcCLB.507811.30 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.511571.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— +2 more OG7
TcCLB.504137.10 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
TcCLB.509777.100 ⚠
ubiquitin-activating enzyme, putative
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.508585.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507711.320 ⚠
DNA mismatch repair protein MSH2, putative
— OG7
TcCLB.504147.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507929.20 ⚠
co-chaperone GrpE, putative
— OG7
TcCLB.508465.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506135.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509551.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508539.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506289.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510747.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510323.10 ⚠
protein kinase, putative
— OG7
TcCLB.507747.220 ⚠
protein farnesyltransferase, putative
— OG7
TcCLB.511217.160 ⚠
WW domain containing protein, putative
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.510741.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511577.50 ⚠
endo-beta-N-acetylglucosaminidase, putative
— OG7
TcCLB.506885.380 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510101.210 ⚠
PUB domain containing protein, putative
— OG7
TcCLB.506375.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.466823.10 ⚠
Checkpoint protein HUS1, putative
— OG7
TcCLB.506755.279 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506693.4 ⚠
eukaryotic translation initiation factor 2 su
— OG7
TcCLB.507099.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509153.110 ⚠
hypothetical protein
— OG7
TcCLB.506829.10 ⚠
Dyggve-Melchior-Clausen syndrome protein, put
— OG7
TcCLB.507809.110 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.507099.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506659.30 ⚠
glutathione synthetase, putative
— OG7
TcCLB.504055.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507611.300 ⚠
RNA-binding protein 14
— OG7
TcCLB.509103.10 ⚠
pre-mRNA splicing factor 19, putative
— OG7
TcCLB.511127.110 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
TcCLB.506739.50 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TcCLB.504625.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509597.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510749.4 ⚠
ubiquitin-protein ligase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.