TcCLB.509551.140

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_108008 OG7: OG7_0013020 184 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 184 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— +1 more Both
TcCLB.508241.120 ⚠
rrp44p homologue, putative
— Both
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— Both
TcCLB.506925.260
Atypical serine/threonine protein kinase BUD3
— Both
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— Both
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— Both
TcCLB.506863.10
alanyl-tRNA synthetase, putative
— Both
TcCLB.506363.90 ⚠
amidohydrolase, putative
— Both
TcCLB.506363.70 ⚠
amidohydrolase, putative
— Both
TcCLB.429257.10
Gar1/Naf1 RNA binding region, putative
— Both
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— Both
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcCLB.511143.6 ⚠
protein kinase, putative (fragment)
— OG6
TcCLB.511141.30 ⚠
protein kinase, putative
— OG6
TcCLB.511369.5 ⚠
elongation factor 1-alpha, putative (fragment
— OG7
TcCLB.510877.55 ⚠
acyl-CoA binding protein, putative
— OG7
TcCLB.511369.30 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.511369.20 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.508949.4 ⚠
elongation factor 1-alpha (ef-1-alpha), putat
— OG7
TcCLB.508041.60 ⚠
eukaryotic release factor 3, putative
— OG7
TcCLB.506953.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511369.10 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.506517.149 ⚠
Acyl CoA binding protein, putative
— OG7
TcCLB.510249.14 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511911.71 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506287.30 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
TcCLB.506773.44 ⚠
cytochrome b5, putative
— OG7
TcCLB.507047.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506753.110 ⚠
cytochrome b5-like protein, putative
— OG7
TcCLB.504431.109 ⚠
cytochrome b5, putative
— OG7
TcCLB.503653.60 ⚠
cytochrome b-domain protein, putative
— OG7
TcCLB.508271.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504153.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506127.20 ⚠
mRNA export factor MEX67
— OG7
TcCLB.504153.300 ⚠
GTPase protein, putative
— OG7
TcCLB.506287.150 ⚠
GTP-binding protein, putative
— OG7
TcCLB.510609.30 ⚠
GTPase, putative
— OG7
TcCLB.506265.160
hypothetical protein, conserved
— OG7
TcCLB.504867.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508973.50 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.511571.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.507811.30 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.503479.49 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcCLB.506505.40 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.506467.40 ⚠
serine/threonine protein kinase, putative
— OG7
TcCLB.508463.20 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.