TcCLB.508949.4

elongation factor 1-alpha (ef-1-alpha), putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100227 OG7: OG7_0001444 118 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 118 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511801.60 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504137.80 ⚠
adenylyl cyclase-associated protein, putative
— OG7
TcCLB.509551.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506375.60 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.504213.20 ⚠
Protein of unknown function (DUF1253), putati
— OG7
TcCLB.508169.69 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcCLB.506733.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510181.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510719.310 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.504883.50 ⚠
tRNA synthetases class II (A)/Threonyl and Al
— OG7
TcCLB.505843.40 ⚠
E1-like ubiquitin-activating enzyme, putative
— OG7
TcCLB.511555.80 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
TcCLB.503671.30 ⚠
leucine-rich repeat-containing protein
— OG7
TcCLB.511127.110 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
TcCLB.506375.10 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507735.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506289.60 ⚠
Cupin-like domain containing protein, putativ
— OG7
TcCLB.510101.140 ⚠
pyruvate phosphate dikinase, putative
— OG7
TcCLB.434931.10 ⚠
paraxonemal rod protein PAR2, putative
— OG7
TcCLB.511215.119 ⚠
Paraflagellar rod protein 2
— OG7
TcCLB.508973.50 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.510741.180 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.506363.80 ⚠
N-acyl-L-amino acid amidohydrolase, putative,
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.510431.220 ⚠
ribosome assembly protein RRB1, putative
— OG7
TcCLB.508277.180 ⚠
mismatch repair protein MSH3, putative
— OG7
TcCLB.507841.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506135.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503653.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.482471.19 ⚠
ATP-dependent RNA helicase SUB2, putative (fr
— OG7
TcCLB.511131.50 ⚠
U4/U6 small nuclear ribonuclear protein, puta
— OG7
TcCLB.511585.190 ⚠
Eukaryotic initiation factor 4A-1
— OG7
TcCLB.511139.40 ⚠
ATP-dependent RNA helicase SUB2, putative (fr
— OG7
TcCLB.511753.50 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.511199.9 ⚠
ATP-dependent RNA helicase FAL1, putative (fr
— OG7
TcCLB.511575.100 ⚠
protein transport protein SEC23, putative
— OG7
TcCLB.506249.20 ⚠
protein transport protein Sec23A, putative
— OG7
TcCLB.504041.4 ⚠
RNA polymerase I
— OG7
TcCLB.503579.150 ⚠
RNA editing complex protein MP57, putative, R
— OG7
TcCLB.504075.10 ⚠
kinetoplast poly(A) polymerase 1
— OG7
TcCLB.506657.70 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
TcCLB.506933.107 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.