TcCLB.508277.180

mismatch repair protein MSH3, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_105075 OG7: OG7_0001337 21 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 21 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511369.5 ⚠
elongation factor 1-alpha, putative (fragment
— OG7
TcCLB.506933.107 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511369.10 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.503579.150 ⚠
RNA editing complex protein MP57, putative, R
— OG7
TcCLB.504075.10 ⚠
kinetoplast poly(A) polymerase 1
— OG7
TcCLB.508041.60 ⚠
eukaryotic release factor 3, putative
— OG7
TcCLB.506657.70 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
TcCLB.508949.4 ⚠
elongation factor 1-alpha (ef-1-alpha), putat
— OG7
TcCLB.511369.20 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.511369.30 ⚠
elongation factor 1-alpha, putative
— OG7
TcCLB.504041.4 ⚠
RNA polymerase I
— OG7
TcCLB.507275.24
ubiquitin fold modifier protein, putative
— Both
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.510737.110 ⚠
replication factor C, subunit 3, putative
— OG7
TcCLB.511589.160 ⚠
replication factor C, subunit 4, putative
— OG7
TcCLB.508647.40 ⚠
replication factor C, subunit 1, putative
— OG7
TcCLB.511741.30 ⚠
replication factor C, subunit 2, putative
— OG7
TcCLB.506517.100 ⚠
ATPase family associated with various cellula
— OG7
TcCLB.511141.30 ⚠
protein kinase, putative
— OG6
TcCLB.511143.6 ⚠
protein kinase, putative (fragment)
— OG6
TcCLB.507711.320
DNA mismatch repair protein MSH2, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.